Quercetin inhibits vascular superoxide production induced by endothelin-1: Role of NADPH oxidase, uncoupled eNOS and PKC
Chronic administration of the most abundant dietary flavonoid quercetin exerts
antihypertensive effects and improves endothelial function. We have investigated the effects …
antihypertensive effects and improves endothelial function. We have investigated the effects …
[HTML][HTML] Quercetin and isorhamnetin prevent endothelial dysfunction, superoxide production, and overexpression of p47phox induced by angiotensin II in rat aorta
M Sanchez, F Lodi, R Vera, IC Villar, A Cogolludo… - The Journal of …, 2007 - Elsevier
The dietary flavonoid quercetin reduces blood pressure and improves endothelial function in
several rat models of hypertension. We analyzed the effects of quercetin and its methylated …
several rat models of hypertension. We analyzed the effects of quercetin and its methylated …
Dietary flavonoid quercetin stimulates vasorelaxation in aortic vessels
NKH Khoo, CR White, L Pozzo-Miller, F Zhou… - Free Radical Biology …, 2010 - Elsevier
Considerable epidemiological evidence indicates that dietary consumption of moderate
levels of polyphenols decreases both the incidence of cardiovascular disease and the …
levels of polyphenols decreases both the incidence of cardiovascular disease and the …
Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats
M Sánchez, M Galisteo, R Vera, IC Villar… - Journal of …, 2006 - journals.lww.com
Results In SHR, quercetin reduced the increase in blood pressure and heart rate and
enhanced the endothelium-dependent aortic vasodilation induced by acetylcholine, but had …
enhanced the endothelium-dependent aortic vasodilation induced by acetylcholine, but had …
Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta
Epidemiological studies have reported an inverse association between dietary flavonoid
intake and mortality for ischemic heart disease. Quercetin reduces blood pressure and …
intake and mortality for ischemic heart disease. Quercetin reduces blood pressure and …
Red wine polyphenols prevent endothelial dysfunction induced by endothelin-1 in rat aorta: role of NADPH oxidase
R López-Sepúlveda, M Gómez-Guzmán… - Clinical …, 2011 - portlandpress.com
RWPs (red wine polyphenols) exert antihypertensive effects and improve endothelial
function by reducing the plasma levels of ET-1 (endothelin-1) and the subsequent vascular …
function by reducing the plasma levels of ET-1 (endothelin-1) and the subsequent vascular …
Quercetin induces rapid eNOS phosphorylation and vasodilation by an Akt-independent and PKA-dependent mechanism
PG Li, L Sun, X Han, S Ling, W Gan, JW Xu - Pharmacology, 2012 - karger.com
Consumption of the flavonoid quercetin exerts beneficial effects on many chronic diseases.
The mechanisms involved in the vasorelaxant effect of quercetin remain uncertain. In the …
The mechanisms involved in the vasorelaxant effect of quercetin remain uncertain. In the …
Quercetin and its metabolites improve vessel function by inducing eNOS activity via phosphorylation of AMPK
Y Shen, KD Croft, JM Hodgson, R Kyle, ILE Lee… - Biochemical …, 2012 - Elsevier
Quercetin is a major flavonoid in a wide range of fruits and vegetables. Consumption of
quercetin may contribute to a reduction in risk of cardiovascular disease (CVD). Following …
quercetin may contribute to a reduction in risk of cardiovascular disease (CVD). Following …
Endothelial function and cardiovascular disease: effects of quercetin and wine polyphenols
F Perez-Vizcaino, J Duarte… - Free radical …, 2006 - Taylor & Francis
Endothelial dysfunction is an early pathophysiological feature and independent predictor of
poor prognosis in most forms of cardiovascular diseases. Epidemiological studies report an …
poor prognosis in most forms of cardiovascular diseases. Epidemiological studies report an …
Quercetin inhibited endothelial dysfunction and atherosclerosis in apolipoprotein E-deficient mice: critical roles for NADPH oxidase and heme oxygenase-1
M Luo, R Tian, N Lu - Journal of Agricultural and Food Chemistry, 2020 - ACS Publications
NADPH oxidase-dependent superoxide (O2·–) production and oxidative stress play
important roles in endothelial dysfunction and atherosclerosis. Herein, we investigated the …
important roles in endothelial dysfunction and atherosclerosis. Herein, we investigated the …
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