Many studies have focused on defining the network of brain structures involved in normal
physiological pain. The different dimensions of pain perception (ie, sensory discriminative …

Acute pain serves as a protective mechanism that alerts us to potential tissue damage and
drives a behavioural response that removes us from danger. The neural circuitry critical for …

The brain transforms nociceptive input into a complex pain experience comprised of
sensory, affective, motivational, and cognitive components. However, it is still unclear how …

Neuroimaging studies have suggested the presence of alterations in the anatomo-functional
properties of the brain of patients with chronic pain. However, investigation of the brain …

Characterizing a reliable, pain-related neural signature is critical for translational
applications. Many prior fMRI studies have examined acute nociceptive pain-related brain …

Chronic pain can be understood not only as an altered functional state, but also as a
consequence of neuronal plasticity. Here we use in vivo structural MRI to compare global …

Different pain types may be encoded in different brain circuits. Here, we examine similarities
and differences in brain processing of visceral and somatic pain. We analyze data from …

MR-based brain imaging technologies provide a suite of functional and structural metrics
that can be used to test hypotheses about the CNS mechanisms underlying pain perception …

Several studies have attempted to characterize morphological brain changes due to chronic
pain. Although it has repeatedly been suggested that longstanding pain induces gray matter …

Background Persistent pain is measured by means of self-report, the sole reliance on which
hampers diagnosis and treatment. Functional magnetic resonance imaging (fMRI) holds …