Two Regions of EpsL Involved in Species-Specific Protein-Protein Interactions with EpsE and EpsM of the General Secretion Pathway inVibrio cholerae
M Sandkvist, JM Keith, M Bagdasarian… - Journal of …, 2000 - Am Soc Microbiol
Extracellular secretion of proteins via the type II or general secretion pathway in gram-
negative bacteria requires the assistance of at least 12 gene products that are thought to …
negative bacteria requires the assistance of at least 12 gene products that are thought to …
Direct Interaction of the EpsL and EpsM Proteins of the General Secretion Apparatus in Vibrio cholerae
M Sandkvist, LP Hough, MM Bagdasarian… - Journal of …, 1999 - Am Soc Microbiol
The general secretion pathway of gram-negative bacteria is responsible for extracellular
secretion of a number of different proteins, including proteases and toxins. This pathway …
secretion of a number of different proteins, including proteases and toxins. This pathway …
The X-ray structure of the type II secretion system complex formed by the N-terminal domain of EpsE and the cytoplasmic domain of EpsL of Vibrio cholerae
J Abendroth, P Murphy, M Sandkvist… - Journal of molecular …, 2005 - Elsevier
Gram-negative bacteria use type II secretion systems for the transport of virulence factors
and hydrolytic enzymes through the outer membrane. These sophisticated multi-protein …
and hydrolytic enzymes through the outer membrane. These sophisticated multi-protein …
Mapping Critical Interactive Sites within the Periplasmic Domain of the Vibrio cholerae Type II Secretion Protein EpsM
TL Johnson, ME Scott, M Sandkvist - Journal of bacteriology, 2007 - Am Soc Microbiol
The type II secretion (T2S) system is present in many gram-negative species, both
pathogenic and nonpathogenic, where it supports the delivery of a variety of toxins …
pathogenic and nonpathogenic, where it supports the delivery of a variety of toxins …
Molecular Analysis of the Vibrio cholerae Type II Secretion ATPase EpsE
JL Camberg, M Sandkvist - Journal of bacteriology, 2005 - Am Soc Microbiol
The type II secretion system is a macromolecular assembly that facilitates the extracellular
translocation of folded proteins in gram-negative bacteria. EpsE, a member of this secretion …
translocation of folded proteins in gram-negative bacteria. EpsE, a member of this secretion …
General secretion pathway (eps) genes required for toxin secretion and outer membrane biogenesis in Vibrio cholerae
M Sandkvist, LO Michel, LP Hough… - Journal of …, 1997 - Am Soc Microbiol
The general secretion pathway (GSP) of Vibrio cholerae is required for secretion of proteins
including chitinase, enterotoxin, and protease through the outer membrane. In this study, we …
including chitinase, enterotoxin, and protease through the outer membrane. In this study, we …
In vivo cross‐linking of EpsG to EpsL suggests a role for EpsL as an ATPase‐pseudopilin coupling protein in the Type II secretion system of Vibrio cholerae
MD Gray, M Bagdasarian, WGJ Hol… - Molecular …, 2011 - Wiley Online Library
The type II secretion system is a multi‐protein complex that spans the cell envelope of Gram‐
negative bacteria and promotes the secretion of proteins, including several virulence factors …
negative bacteria and promotes the secretion of proteins, including several virulence factors …
Interaction between the autokinase EpsE and EpsL in the cytoplasmic membrane is required for extracellular secretion in Vibrio cholerae.
M Sandkvist, M Bagdasarian, SP Howard… - The EMBO …, 1995 - embopress.org
Vibrio cholerae secretes a number of proteins important for virulence, including cholera
toxin. This process requires the products of the eps genes which have homologues in …
toxin. This process requires the products of the eps genes which have homologues in …
Crystal structure of the extracellular protein secretion NTPase EpsE of Vibrio cholerae
MA Robien, BE Krumm, M Sandkvist… - Journal of molecular …, 2003 - Elsevier
Type II secretion systems consist of an assembly of 12–15 Gsp proteins responsible for
transporting a variety of virulence factors across the outer membrane in several pathogenic …
transporting a variety of virulence factors across the outer membrane in several pathogenic …
Docking and Assembly of the Type II Secretion Complex of Vibrio cholerae
SR Lybarger, TL Johnson, MD Gray… - Journal of …, 2009 - Am Soc Microbiol
Secretion of cholera toxin and other virulence factors from Vibrio cholerae is mediated by the
type II secretion (T2S) apparatus, a multiprotein complex composed of both inner and outer …
type II secretion (T2S) apparatus, a multiprotein complex composed of both inner and outer …
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