Efficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary disease

W Szafranski, A Cukier, A Ramirez… - European …, 2003 - Eur Respiratory Soc
The efficacy and safety of budesonide/formoterol in a single inhaler compared with placebo,
budesonide and formoterol were evaluated in patients with moderate-to-severe chronic …

Clinical efficacy with formoterol in the absence of a response to salmeterol: A review

J Kottakis, R Wood, VL Gros… - International journal of …, 2001 - Wiley Online Library
Salmeterol and formoterol are both β2‐agonist bronchodilators with a long duration of action
and are often classified together, yet they are distinctly different in their pharmacology …

Inhaled dry-powder formoterol and salmeterol in asthmatic patients: onset of action, duration of effect and potency

M Palmqvist, G Persson, L Lazer… - European …, 1997 - Eur Respiratory Soc
Salmeterol and formoterol are two long-acting beta2-agonists for inhalation, currently being
used in clinical practice. The aim of the present study was to investigate the onset of action …

Tolerability of short-term, high-dose formoterol in healthy volunteers and patients with asthma

NK Ostrom - Clinical therapeutics, 2003 - Elsevier
Background: Formoterol is a long-acting (≥ 12 hours) beta2-receptor agonist with a rapid
onset of action (1–3 minutes). It is approved in the United States, delivered via a single-dose …

Controversies involving inhaled β-agonists and inhaled corticosteroids in the treatment of asthma

JV Fahy, HA Boushey - Clinics in chest medicine, 1995 - Elsevier
Controversy over the use of inhaled β-ago-nists has dated almost from their introduction as a
treatment for asthma. Their effectiveness as bronchodilators is not disputed, but there is …

β2‐adrenoceptor agonists: current and future direction

M Cazzola, L Calzetta… - British journal of …, 2011 - Wiley Online Library
Despite the passionate debate over the use of β2‐adrenoceptor agonists in the treatment of
airway disorders, these agents are still central in the symptomatic management of asthma …

A comparison of salmeterol with albuterol in the treatment of mild-to-moderate asthma

DS Pearlman, P Chervinsky, C LaForce… - … England Journal of …, 1992 - Mass Medical Soc
Background. An effective, long-acting bronchodilator could benefit patients with asthma who
have symptoms not controlled by antiinflammatory drugs. We compared a new long-acting …

Dose-response curve to salbutamol during acute and chronic treatment with formoterol in COPD

GE La Piana, L Corda, E Bertella… - … Journal of Chronic …, 2011 - Taylor & Francis
Background Use of short-acting β2-agonists in chronic obstructive pulmonary disease
(COPD) during treatment with long-acting β2-agonists is recommended as needed, but its …

Comparison of the relative efficacy of formoterol and salmeterol in asthmatic patients

M Palmqvist, T Ibsen, A Mellen… - American journal of …, 1999 - atsjournals.org
Studies performed on airway smooth muscle in vitro have indicated that salmeterol is a
partial agonist on the β2-receptor in comparison to formoterol. In the present study we …

Long-Term Effects of a Long-Acting β2-Adrenoceptor Agonist, Salmeterol, on Airway Hyperresponsiveness in Patients with Mild Asthma

D Cheung, MC Timmers, AH Zwinderman… - … England Journal of …, 1992 - Mass Medical Soc
Background. Asthma is characterized by hyperresponsiveness of the airways to
bronchoconstrictive stimuli. Long-acting β2-adrenoceptor agonists have been introduced as …