High-Density Lipoproteins and Cardiovascular Disease: The Good, the Bad and the Future

J Julve, JC Escolà-Gil - Biomedicines, 2021 - mdpi.com
Epidemiological studies have shown that low levels of plasma high-density lipoprotein
cholesterol (HDL-C) are associated with increased atherosclerotic cardiovascular disease …

High-density lipoproteins and cardiovascular disease: 2010 update

K Alwaili, Z Awan, A Alshahrani… - Expert review of …, 2010 - Taylor & Francis
High-density lipoprotein-cholesterol (HDL-C) is a continuous inverse cardiovascular risk
factor. The mechanisms by which HDLs protect against atherosclerosis are multiple. The …

[HTML][HTML] High-density lipoprotein: a double-edged sword in cardiovascular physiology and pathophysiology

G Ndrepepa - Journal of Laboratory and Precision Medicine, 2021 - jlpm.amegroups.org
High-density lipoprotein (HDL) plays a central role in vascular biology. HDL participates in
multiple pathways that may be involved in the development of atherosclerosis and coronary …

High density lipoproteins (HDLs) and atherosclerosis; the unanswered questions

P Barter, J Kastelein, A Nunn, R Hobbs, FFE Board - Atherosclerosis, 2003 - Elsevier
The concentration of high density lipoprotein-cholesterol (HDL-C) has been found
consistently to be a powerful negative predictor of premature coronary heart disease (CHD) …

High-density lipoprotein: epidemiology, metabolism, and antiatherogenic effects

PP Toth - Disease-a-month, 2001 - Elsevier
Conclusion HDL is clearly a functionally versatile molecule mediating a variety of molecular
processes protective against atherosclerosis. Mechanistic detail continues to greatly enrich …

Novel insights from human studies on the role of high-density lipoprotein in mortality and noncardiovascular disease

CM Madsen, A Varbo… - … , thrombosis, and vascular …, 2021 - Am Heart Assoc
The vast majority of research about HDL (high-density lipoprotein) has for decades revolved
around the possible role of HDL in atherosclerosis and its therapeutic potential within …

High-density lipoproteins: a therapeutic target for atherosclerotic cardiovascular disease

M Gomaraschi, L Calabresi… - Expert Opinion On …, 2006 - Taylor & Francis
Despite great progress being made during the last two decades in cardiovascular disease
prevention, especially by lowering low-density lipoprotein-cholesterol with statins …

High density lipoprotein in atherosclerosis and coronary heart disease: where do we stand today?

E Zvintzou, DS Karampela, A Vakka, E Xepapadaki… - Vascular …, 2021 - Elsevier
Epidemiological studies during the last five years suggest that a relation between high
density lipoprotein cholesterol (HDL-C) levels and the risk for cardiovascular disease (CVD) …

High-density lipoprotein: is the good cholesterol turning bad?

A Inankur, SJ Nicholls, A Jahangiri - Current Cardiovascular Risk Reports, 2011 - Springer
Low high-density lipoprotein cholesterol (HDL-C) is the most prevalent lipid abnormality in
patients with known coronary heart disease (CHD). Since the 1960 s, epidemiologic studies …

High-density lipoproteins: biology, epidemiology, and clinical management

HY Choi, A Hafiane, A Schwertani, J Genest - Canadian Journal of …, 2017 - Elsevier
High-density lipoproteins (HDLs) have multiple pleiotropic effects against arteriosclerosis.
Most are independent of the cholesterol mass within HDL particles. Yet, HDL cholesterol …