Sepsis is one of the most common deadly diseases. Despite its remarkable incidence, and
despite the progress which has been made in understanding this complex syndrome, for …

Background Our current understanding of the pathophysiology and management of sepsis is
associated with a lack of progress in clinical trials, which partly reflects insufficient …

Sepsis and sepsis-associated multi-organ failure are major challenges for scientists and
clinicians and are a tremendous burden for health-care systems. Despite extensive basic …

Sepsis is a life-threatening condition originating as a result of systemic blood infection
causing, one or more organ damage due to the dysregulation of the immune response. In …

Long before van Leeuwenhoek peered through his microscope to describe bacteria in 1676,
microbial infections have been an enduring cause of human death. Although the evolution of …

Sepsis is characterized as a life-threatening organ dysfunction syndrome that is caused by a
dysregulated host response to infection. The main etiological causes of sepsis are bacterial …

Sepsis, severe sepsis, and septic shock are stages of increasing severity of the systemic
host response to bloodstream infections. 1, 2 Since the 1980s, the epidemiologic burden of …

Sepsis is an infection-initiated systemic inflammatory syndrome with an estimated incidence
of 18 million cases annually worldwide. Despite advances in intensive care and supportive …

2. Mayr FB, Yende S, Angus DC. Epidemiology of severe sepsis. Virulence 2014; 5: 4-11;
PMID: 24335434; http://dx. doi. org/10.4161/viru. 27372 3. Angele MK, Pratschke S, Hubbard …

Introduction Precision medicine is a medical model in which decisions, practices,
interventions and therapies are tailored to the individual patient based on their predicted …