Sepsis is a major source of mortality and morbidity globally. Accurately diagnosing sepsis
remains challenging due to the heterogeneous nature of the disease, and delays in …

Sepsis is a clinical syndrome that results from the dysregulated inflammatory response to
infection that leads to organ dysfunction. The resulting losses to society in terms of financial …

Sepsis remains the leading cause of death in most intensive care units. Advances in
understanding the immune response to sepsis provide the opportunity to develop more …

The definition of sepsis continues to be as dynamic as the management strategies used to
treat this. Sepsis-3 has replaced the earlier systemic inflammatory response syndrome …

Immune therapy to ease the burden of sepsis has thus far failed to consistently improve
patient outcomes. Advances in cancer immune therapy and awareness that prolonged …

Pathogenic sepsis is not a monolithic condition. Three major types of sepsis exist within this
category: bacterial, viral, and fungal, each with its own mechanism of action. While similar in …

Beside many efforts to improve outcome, sepsis is still one of the most frequent causes of
death in critically ill patients. It is the most common condition with high mortality in intensive …

Sepsis is a complex condition characterized by the simultaneous activation of inflammation
and coagulation in response to microbial insult. These events manifest as systemic …

Sepsis has been around since the dawn of time, having been described for more than 2000
years, although clinical definitions are recent. The consensus sepsis definitions have …

The diseases of critical illness are rooted in the response of the host to clinical interventions
that have thwarted imminent death. Sepsis—the clinical syndrome that embodies the …