Dysregulation of the microbiota-brain axis during long-term exposure to polystyrene nanoplastics in rats and the protective role of dihydrocaffeic acid

W Jiang, C Hu, Y Chen, Y Li, X Sun, H Wu… - Science of The Total …, 2023 - Elsevier
Polystyrene nano-plastics (PS-NPs) can be accumulated in the food chain and can
penetrate biological barriers to affect multiple physiological functions. However, the adverse …

[HTML][HTML] Polystyrene micro-and nanoparticles exposure induced anxiety-like behaviors, gut microbiota dysbiosis and metabolism disorder in adult mice

X Chen, L Xu, Q Chen, S Su, J Zhuang… - … and Environmental Safety, 2023 - Elsevier
Plastics have been proven to be a potential threat to the ecosystem, and their toxicity
mechanism is still uncertain. In the ecological environment, plastics can be degraded into …

Exposure to different surface-modified polystyrene nanoparticles caused anxiety, depression, and social deficit in mice via damaging mitochondria in neurons

Y Ma, D Xu, Z Wan, Z Wei, Z Chen, Y Wang… - Science of The Total …, 2024 - Elsevier
Nanoplastics (NPs) are unavoidable hazardous materials that result from the human
production and use of plastics. While there is evidence that NPs can bioaccumulate in the …

Epigallocatechin-3-gallate ameliorates polystyrene microplastics-induced anxiety-like behavior in mice by modulating gut microbe homeostasis

JZ Yang, KK Zhang, Y Liu, XW Li, LJ Chen… - Science of the Total …, 2023 - Elsevier
Polystyrene microplastics (PS-MPs) have emerged as a concerning pollutant in modern
society due to their widespread production and usage. Despite ongoing research efforts, the …

The gut-brain axis involved in polystyrene nanoplastics-induced neurotoxicity via reprogramming the circadian rhythm-related pathways

H Kang, W Zhang, J Jing, D Huang, L Zhang… - Journal of Hazardous …, 2023 - Elsevier
The production of plastic is still increasing globally, which has led to an increasing number
of plastic particles in the environment. Nanoplastics (NPs) can penetrate the blood-brain …

[HTML][HTML] Oxidized/unmodified-polyethylene microplastics neurotoxicity in mice: Perspective from microbiota-gut-brain axis

J Wang, Y Yang, Y Shi, L Wei, L Gao, M Liu - Environment International, 2024 - Elsevier
Microplastics (MPs) are inevitably oxidized in the environment, and their potential toxicity to
organisms has attracted wide attention. However, the neurotoxicity and mechanism of …

Polystyrene nanoplastics toxicity to zebrafish: dysregulation of the brain–intestine–microbiota axis

M Teng, X Zhao, C Wang, C Wang, JC White, W Zhao… - ACS …, 2022 - ACS Publications
In animal species, the brain–gut axis is a complex bidirectional network between the
gastrointestinal (GI) tract and the central nervous system (CNS) consisting of numerous …

Microbiota-mediated metabolic perturbations in the gut and brain of mice after microplastic exposure

SH Lee, WY Lin, TJ Cheng - Chemosphere, 2024 - Elsevier
Microplastics (MPs), emerging environmental toxicants, have drawn attention because of
their wide distribution in the environment. Exposure to MPs induces gut microbiota …

Impact of food matrices on the characteristics and cellular toxicities of ingested nanoplastics in a simulated digestive tract

Z Li, Y Huang, Y Zhong, B Liang, X Yang… - Food and Chemical …, 2023 - Elsevier
Microplastic and nanoplastic (MNP) pollution has become a major global food safety
concern. MNPs can interact with food matrices, and their passage through the …

Integrated fecal microbiome and metabolome analysis explore the link between polystyrene nanoplastics exposure and male reproductive toxicity in mice

X Fu, L Liu, H Han, Y Li, S Si, B Xu, W Dai… - Environmental …, 2023 - Wiley Online Library
Abstract Microplastics (MPs) and nanoplastics (NPs) are novel environmental pollutants that
are ubiquitous in the environment and everyday life. NPs can easily enter the tissues and …