Tyrosine hydroxylase (TH) in freshly prepared 45,000 g supernatant from rat striatum was
fractionated by DEAE-cellulose chromatography. The elution was made with 2 vols. of buffer …

The subcellular distribution of the protein tyrosine hydroxylase (TH) after fractionation of rat
brain tissue was studied by a sensitive technique of immunoblot quantification in the …

The centrally active muscarinic agonist, oxotremorine, elicited an up to 2-fold dose-
dependent (0.25-1.5 mg/kg) increase in the activity of tyrosine hydroxylase (TH) in the rat …

Soluble tyrosine hydroxylase from human pheochromocytoma, bovine adrenal medulla and
rat striatum can be activated by Mg 2+, ATP and cyclic AMP. In pheochromocytoma, this …

Tyrosine hydroxylase activities in 12 neuroblastoma tissues from 8 patients and 4 human
adrenal glands from 3 autopsied cases were determined after partial purification of the …

There is general agreement as to the properties of tyrosine hydroxylase from the adrenal
medulla, but the properties of brain tyrosine hydroxylase are more controversial. This is …

We have reported previously that tyrosine hydroxylase in the crude extract from rat striatum
exists in the inactive form showing almost no activity at the physiological pH and that the …

MATERIALS AND METHODS Specific antiserum to bovine adrenal TH and antiserum to 5-
HT were used in the present experiment. Antiserum to TH was raised in rabbits and its …

A sensitive, radiochemical assay for tyrosine hydroxylase in rat brain is described. The
enzyme is stimulated by catalase, dihydropteridine reductase and ferrous ion; maximal …

The peroxidase‐antiperoxidase (PAP) technique is used to determine the cellular
localization of tyrosine hydroxylase in the human fetal nervous system. Antiserum to trypsin …