The neurobiology of suicide risk: a review for the clinician

JJ Mann, M Oquendo… - Journal of Clinical …, 1999 - legacy.psychiatrist.com
Suicidal behavior has neurobiological determinants independent of the psychiatric illnesses
with which it is associated. We have found that some patients with major depression are …

Suicide, serotonin and the brain.

C Van Heeringen - Crisis: The Journal of Crisis Intervention and …, 2001 - psycnet.apa.org
The involvement of impaired serotonergic functioning in the development of suicidal
behavior is one of the best documented findings in biological psychiatry. It is, however, less …

Understanding the neurobiology of suicidal behavior

M Kamali, MA Oquendo, JJ Mann - Depression and anxiety, 2001 - Wiley Online Library
Our current knowledge about the neurobiology of suicide is still limited. Technical limitations
and the complexity of the CNS are major obstacles. However, there is evidence for a …

Biological basis of suicide and suicidal behavior

GN Pandey - Bipolar disorders, 2013 - Wiley Online Library
Objective Suicide is a major public health concern as each year 30000 people die by
suicide in the USA alone. In the teenage population, it is the second leading cause of death …

Positron emission tomographic imaging of the serotonergic system and prediction of risk and lethality of future suicidal behavior

MA Oquendo, H Galfalvy, GM Sullivan, JM Miller… - JAMA …, 2016 - jamanetwork.com
Importance Biomarkers that predict suicidal behavior, especially highly lethal behavior, are
urgently needed. In cross-sectional studies, individuals with depression who attempt suicide …

Localized alterations in pre-and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims

V Arango, MD Underwood, AV Gubbi, JJ Mann - Brain research, 1995 - Elsevier
Altered serotonin indices have been reported in the brain of suicide victims. We sought to
localize the changes in presynaptic and postsynaptic serotonin receptors and identify an …

Neural substrates of suicide and suicidal behaviour: from a neuroimaging perspective

YH Balcioglu, S Kose - Psychiatry and Clinical …, 2018 - Taylor & Francis
In this article, we have reviewed neuroimaging studies on the neural circuitry associated
with suicidal behaviour in order to identify the neural substrates of suicidal behaviour. The …

Positron emission tomography of regional brain metabolic responses to a serotonergic challenge and lethality of suicide attempts in major depression

MA Oquendo, GPA Placidi, KM Malone… - Archives of general …, 2003 - jamanetwork.com
Background Lower serotonergic activity correlates with high-lethality suicide attempts in
major depression. Postmortem studies of serotonin receptors in suicides localize changes to …

The psychology and neurobiology of suicidal behavior

TE Joiner Jr, JS Brown, LRR Wingate - Annu. Rev. Psychol., 2005 - annualreviews.org
Suicide is a leading cause of death, but it is not well understood or well researched. Our
purpose in this review is to summarize extant knowledge on neurobiological and …

The neurobiology of suicide and suicidality

K Van Heeringen - The Canadian Journal of Psychiatry, 2003 - journals.sagepub.com
Objective: To investigate the current state of knowledge regarding the neurobiology of
suicide and suicidality. Method: The literature on the neurobiology of suicidality and suicide …