m6A-TSHub: Unveiling the Context-Specific m6A Methylation and m6A-Affecting Mutations in 23 Human Tissues
As the most pervasive epigenetic marker present on mRNAs and long non-coding RNAs
(lncRNAs), N 6-methyladenosine (m6A) RNA methylation has been shown to participate in …
(lncRNAs), N 6-methyladenosine (m6A) RNA methylation has been shown to participate in …
Link between m6A modification and cancers
ZX Liu, LM Li, HL Sun, SM Liu - Frontiers in bioengineering and …, 2018 - frontiersin.org
N6-methyladenosine (m6A) epitranscriptional modification has recently gained much
attention. Through the development of m6A sequencing, the molecular mechanism and …
attention. Through the development of m6A sequencing, the molecular mechanism and …
[HTML][HTML] The essential roles of m6A modification in osteogenesis and common bone diseases
Y Gu, Y Song, Y Pan, J Liu - Genes & Diseases, 2024 - Elsevier
Abstract N6-methyladenosine (m 6 A) is the most prevalent modification in the eukaryotic
transcriptome and has a wide range of functions in coding and noncoding RNAs. It affects …
transcriptome and has a wide range of functions in coding and noncoding RNAs. It affects …
Dynamic and reversible RNA N6‐methyladenosine methylation
N6‐methyladenosine (m6A) is the most abundant internal chemical modification in
eukaryotic messenger RNAs (mRNAs). The discovery in 2011 that m6A is reversed by the fat …
eukaryotic messenger RNAs (mRNAs). The discovery in 2011 that m6A is reversed by the fat …
The roles of N6-methyladenosine methylation in the regulation of bone development, bone remodeling and osteoporosis
Y Li, L Meng, B Zhao - Pharmacology & therapeutics, 2022 - Elsevier
Abstract N 6-methyladenosine (m 6 A), a novel epitranscriptomic RNA modification, plays
crucial roles in a variety of biological processes and diseases. Recently, there are growing …
crucial roles in a variety of biological processes and diseases. Recently, there are growing …
Relevance of N6-methyladenosine regulators for transcriptome: Implications for development and the cardiovascular system
WK Sweaad, FM Stefanizzi… - Journal of Molecular and …, 2021 - Elsevier
Abstract N6-methyladenosine (m6A) is the most abundant and well-studied internal
modification of messenger RNAs among the various RNA modifications in eukaryotic cells …
modification of messenger RNAs among the various RNA modifications in eukaryotic cells …
Biological functions of m6A methyltransferases
J Gu, Y Zhan, L Zhuo, Q Zhang, G Li, Q Li, S Qi, J Zhu… - Cell & bioscience, 2021 - Springer
M 6 A methyltransferases, acting as a writer in N6-methyladenosine, have attracted wide
attention due to their dynamic regulation of life processes. In this review, we first briefly …
attention due to their dynamic regulation of life processes. In this review, we first briefly …
Novel insights into the role of N6-methyladenosine RNA modification in bone pathophysiology
Thus far, there are more than known 150 modifications to RNA, in which common internal
modifications of mRNA include N6-methyladenosine (m6A), N1-methyladenosine, and 5 …
modifications of mRNA include N6-methyladenosine (m6A), N1-methyladenosine, and 5 …
m6A Modification in Mammalian Nervous System Development, Functions, Disorders, and Injuries
J Yu, Y She, SJ Ji - Frontiers in cell and developmental biology, 2021 - frontiersin.org
N 6-methyladenosine (m6A) modification, as the most prevalent internal modification on
mRNA, has been implicated in many biological processes through regulating mRNA …
mRNA, has been implicated in many biological processes through regulating mRNA …
RNA m6A modification and its function in diseases
J Tong, RA Flavell, HB Li - Frontiers of medicine, 2018 - Springer
Abstract N 6-methyladenosine (m 6 A) is the most common post-transcriptional RNA
modification throughout the transcriptome, affecting fundamental aspects of RNA …
modification throughout the transcriptome, affecting fundamental aspects of RNA …