The periconceptional period of mammalian development has been identified as an early
'developmental window'during which environmental conditions may influence the pattern of …

It is now well established that the environment to which we are exposed during fetal and
neonatal life can have a long-term impact on our health. This has been termed the …

Fetal growth is determined by the interaction between the environment and the fetal
genome. The fetal environment, in turn, is determined by the maternal environment and by …

The concept emerging from Professor David Barker's seminal research on the
developmental origins of later-life disease has progressed in many directions since it was …

The early embryo and periconceptional period is a window during which environmental
factors may cause permanent change in the pattern and characteristics of development …

Many epidemiological studies indicate that environmental conditions during embryonic and
fetal development can have an impact on health at adulthood. Animal studies clearly …

Abstract The Developmental Origins of Health and Disease hypothesis describes how early
life environmental factors influence development in a way that impacts later health and …

For decades it has been postulated that the period in utero may be critical in modifying the
risk of adult-onset disease, although only recently has epigenetic change emerged as the …

Numerous epidemiological studies have shown that exposure to an adverse environment in
early life is associated with a substantially increased risk of later disease; a phenomenon …

Epidemiological and experimental studies have shown that the peri-conception period,
pregnancy, and infancy are windows of particular sensibility to environmental clues which …