[HTML][HTML] A plumieridine-rich fraction from Allamanda polyantha inhibits chitinolytic activity and exhibits antifungal properties against Cryptococcus neoformans

E Silva e Souza, VA Barcellos, N Sbaraini… - Frontiers in …, 2020 - frontiersin.org
Cryptococcosis is a fungal infection caused mainly by the pathogenic yeasts Cryptococcus
neoformans and Cryptococcus gattii. The infection initiates with the inhalation of propagules …

Antifungal activity of Allamanda polyantha seed extract and its iridoids promote morphological alterations in Cryptococcus spp.

FR Bresciani, L Santi, WO Beys‐da‐Silva… - Archiv der …, 2020 - Wiley Online Library
Cryptococcosis, caused by Cryptococcus spp., is an invasive fungal infection of the central
nervous system, associated with high mortality, affecting mainly immunocompromised …

[HTML][HTML] Globospiramine Exhibits Inhibitory and Fungicidal Effects against Candida albicans via Apoptotic Mechanisms

JAH Manzano, S Brogi, V Calderone, APG Macabeo… - Biomolecules, 2024 - mdpi.com
Candidiasis is considered an emerging public health concern because of the occurrence of
drug-resistant Candida strains and the lack of an available structurally diverse antifungal …

Discovery of New Tricyclic Oxime Sampangine Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcosis and Candidiasis

W Yang, R Liu, Z Li, J Tu, D Xu, N Liu… - Journal of Medicinal …, 2024 - ACS Publications
Cryptococcus neoformans (C. neoformans) and Candida albicans (C. albicans) are
classified as the critical priority groups among the pathogenic fungi, highlighting the urgent …

[HTML][HTML] Anti-Candida albicans Activity of Ononin and Other Secondary Metabolites from Platonia Insignis MART

AF Silva, JR Farias, DCG Franco, AA Galiza, EP Motta… - Metabolites, 2022 - mdpi.com
Candida albicans is a human pathogen that is part of the healthy microbiome. However, it is
often associated with opportunistic fungal infections. The treatment of these infections is …

[HTML][HTML] Annona muricata Leaf as an Anti-Cryptosporidial Agent: An In Silico Molecular Docking Analysis and In Vivo Studies

ES El-Wakil, HF Abdelmaksoud, MH Wakid… - Pharmaceuticals, 2023 - mdpi.com
Cryptosporidiosis is a serious parasitic diarrheal disease linked to the occurrence of
colorectal cancer in immunocompromised patients. The FDA-approved drug nitazoxanide …

[HTML][HTML] Antifungal combination of ethyl acetate extract of Poincianella pluviosa (DC.) LP queiros stem bark with amphotericin B in Cryptococcus neoformans

GM Andriani, AEB Morguette, LFA Spoladori… - Frontiers in …, 2021 - frontiersin.org
Cryptococcus neoformans is the leading cause of cryptococcosis, an invasive and
potentially fatal infectious disease. Therapeutic failures are due to the increase in antifungal …

[HTML][HTML] Biocontrol potential of Chitinophaga flava HK235 producing antifungal-related peptide chitinocin

DY Kim, JW Han, JW Lee, B Kim, YS Kim… - Frontiers in …, 2023 - frontiersin.org
Botrytis cinerea is a necrotrophic fungal pathogen with an extremely broad host range,
causing significant economic losses in agricultural production. In this study, we discovered a …

[HTML][HTML] Chemical profiling of Verbena officinalis and assessment of its anti-cryptosporidial activity in experimentally infected immunocompromised mice

ES El-Wakil, MAM El-Shazly, AM El-Ashkar… - Arabian Journal of …, 2022 - Elsevier
Cryptosporidiosis is a global zoonotic infection that causes water-borne epidemics of
diarrhea. Nevertheless, there are few available therapies for cryptosporidiosis. However, the …

[HTML][HTML] Identification of novel drug targets and screening potential drugs against Cryptococcus gattii: an in silico approach

TB Robin, NA Rani, N Ahmed, AA Prome… - Informatics in Medicine …, 2023 - Elsevier
Cryptococcus gattii is an emerging fungal pathogen responsible for causing cryptococcosis,
which is an infectious disease with a global prevalence and a wide range of clinical …