Anticandidial and anticryptococcal activity of Euphorbia fusiformis, a rare medicinal plant

D Natarajan, N Nagamurugan… - World journal of …, 2007 - Springer
The present work demonstrates the screening of extracts of the rare medicinal herb
Euphorbia fusiformis for antifungal activity. The main aim was to investigate its antifungal …

The Metschnikowia pulcherrima Clade as a Model for Assessing Inhibition of Candida spp. and the Toxicity of Its Metabolite, Pulcherrimin

D Kregiel, KH Czarnecka-Chrebelska, H Schusterová… - Molecules, 2023 - mdpi.com
Candidiasis is one of the most frequent infections worldwide. In this study, the antimicrobial
properties of six strains belonging to the Metschnikowia pulcherrima clade were evaluated …

Antifungal Activity and Mode of Action of Miltefosine Against Clinical Isolates of Candida krusei

Y Wu, M Wu, J Gao, C Ying - Frontiers in Microbiology, 2020 - frontiersin.org
Candida krusei attracts attention from medical professionals mainly for its intrinsic resistance
to fluconazole and the limited number of drugs available to treat C. krusei vulvovaginal …

Discovery of Novel Anti-cryptosporidial Activities From Natural Products by in vitro High-Throughput Phenotypic Screening

Z Jin, J Ma, G Zhu, H Zhang - Frontiers in Microbiology, 2019 - frontiersin.org
Cryptosporidium parvum is a globally distributed zoonotic protozoan parasite of both
medical and veterinary importance. Nitazoxanide is the only FDA-approved drug to treat …

Antibacterial and antifungal activities of isoquinoline alkaloids of the Papaveraceae and Fumariaceae families and their implications in structure–activity relationships

FG Avci, B Atas, GG Toplan, C Gurer… - Studies in Natural …, 2021 - Elsevier
Historically, plants with a wide range of natural products they possess have long served as
important sources of therapeutical agents. Unfortunately, progress in the construction of …

Fungicidal Activity of Recombinant Javanicin against Cryptococcus neoformans Is Associated with Intracellular Target(s) Involved in Carbohydrate and Energy …

S Orrapin, S Roytrakul, N Phaonakrop, S Thaisakun… - Molecules, 2021 - mdpi.com
The occurrence of Cryptococcus neoformans, the human fungal pathogen that primarily
infects immunocompromised individuals, has been progressing at an alarming rate. The …

Methylxanthine inhibit fungal chitinases and exhibit antifungal activity

K Tsirilakis, C Kim, AG Vicencio, C Andrade… - Mycopathologia, 2012 - Springer
Chitinases are necessary for fungal cell wall remodeling and cell replication.
Methylxanthines have been shown to competitively inhibit family 18 chitinases in vitro. We …

Ligand-based analysis of the antifungal potential of phytosterols and triterpenes isolated from Cryptostegia grandiflora against Candida auris FKBP12

AB Belarmino, DS de Sousa, CHA Roberto… - Steroids, 2024 - Elsevier
Candida auris, a pathogenic fungus, has posed significant challenges to conventional
medical treatments due to its increasing resistance to antifungal agents. Consequently, due …

Holothurin compound from sea cucumber (Holothuria sp.) as antifungal alternative against Candida infections

S Handayani, N Nurdiana, S Winarsih… - … Macedonian Journal of …, 2022 - oamjms.eu
BACKGROUND: The previous studies have identified chemical compounds in sea
cucumbers that have antifungal properties. However, further information on the underlying …

Analysis of the Fungal Virulence of Cryptococcus and Exploration of Novel Antifungals Against Cryptococcosis

B Zhai - 2014 - oaktrust.library.tamu.edu
Cryptococcosis is one of the leading causes of the deaths among AIDS patients. The high
mortality rates of cryptococcosis are mainly due to inadequate information of its major …