The Anti-Virulence Effect of Vismia guianensis against Candida albicans and Candida glabrata

EP Motta, JR Farias, AAC Costa, AF Silva… - Antibiotics, 2022 - mdpi.com
In folk medicine, Vismia guianensis is used to treat skin diseases and mycoses in the
Amazon region. We evaluated the anti-Candida activity of the hydroalcoholic extract from the …

Novel antifungal compounds discovered in medicines for malaria venture's malaria box

EH Jung, DJ Meyers, J Bosch, A Casadevall - Msphere, 2018 - Am Soc Microbiol
Similarities in fungal and animal cells make antifungal discovery efforts more difficult than
those for other classes of antimicrobial drugs. Currently, there are only three major classes …

Anti-protozoal activity of extracts from chicory (Cichorium intybus) against Cryptosporidium parvum in cell culture

ID Woolsey, AH Valente, AR Williams… - Scientific Reports, 2019 - nature.com
Cryptosporidium spp. are responsible for severe public health problems and livestock
production losses. Treatment options are limited to only one drug available for human and …

A Vanillin Derivative Causes Mitochondrial Dysfunction and Triggers Oxidative Stress in Cryptococcus neoformans

JH Kim, HO Lee, YJ Cho, J Kim, J Chun, J Choi, Y Lee… - PloS one, 2014 - journals.plos.org
Vanillin is a well-known food and cosmetic additive and has antioxidant and antimutagenic
properties. It has also been suggested to have antifungal activity against major human …

Miltefosine exhibits fungicidal activity through oxidative stress generation and Aif1 activation in Candida albicans

Y Wu, Y Chen, H Lu, C Ying - International Journal of Antimicrobial Agents, 2023 - Elsevier
Invasive candidiasis is the most common and serious fungal disease worldwide, and the
development of antifungal drug resistance in Candida spp. is an emerging problem …

Special Issue “Drug Discovery of Antiprotozoal Agents”

FJB Mendonça-Junior - Pharmaceuticals, 2024 - mdpi.com
Protozoal diseases, such as leishmaniasis, malaria, African sleeping sickness, Chagas
disease, amoebiasis, giardiasis, cryptococcosis, and toxoplasmosis (among others), affect …

The aminoalkylindole BML-190 negatively regulates chitosan synthesis via the cyclic AMP/protein kinase A1 pathway in Cryptococcus neoformans

BT Maybruck, WC Lam, CA Specht, MXG Ilagan… - Mbio, 2019 - Am Soc Microbiol
Cryptococcus neoformans can cause fatal meningoencephalitis in patients with AIDS or
other immunocompromising conditions. Current antifungals are suboptimal to treat this …

[图书][B] Isolation and characterization of compounds active against Cryptococcus neoformans from Maytenus undata (Thunb.) Blakelock (Celastraceae) leaves

TA Mokoka - 2008 - search.proquest.com
Microbial infections are a major threat to public health particularly in developing countries
due to the relative unavailability of medicine and the emergence of widespread drug …

Plumieride as a novel anti-fungal and anti-inflammatory iridoid against superficial candidiasis in mice

RA El-Shiekh, MR Meselhy, R Elshimy… - … Medicine and Therapies, 2024 - Springer
In the past few decades, there has been a notable rise in the occurrence of several types of
candidiasis. Candida albicans is the most common cause of superficial fungal infections in …

Anthelmintic Potential of Thymoquinone and Curcumin on Fasciola gigantica

R Ullah, A Rehman, MF Zafeer, L Rehman, YA Khan… - PloS one, 2017 - journals.plos.org
Fasciolosis an economically important global disease of ruminants in the temperate and
tropical regions, caused by Fasciola hepatica and F. gigantica, respectively, also poses a …