IL-10 is an anti-inflammatory cytokine. During infection it inhibits the activity of Th1 cells, NK
cells, and macrophages, all of which are required for optimal pathogen clearance but also …

The generation of an effective immune response against an infection while also limiting
tissue damage requires a delicate balance between pro-and anti-inflammatory responses …

Abstract Interleukin-10 (IL-10), a cytokine with anti-inflammatory properties, has a central
role in infection by limiting the immune response to pathogens and thereby preventing …

Macrophages play a central role in infections, as a target for pathogens and in activation of
the immune system. Interleukin-10 (IL-10), a cytokine produced by macrophages, is a potent …

The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …

IL-10 plays an essential part in controlling inflammation and instructing adaptive immune
responses. Consequently, dysregulation of IL-10 is linked with susceptibility to numerous …

Since its initial description as a Th2-cytokine antagonistic to interferon-alpha and
granulocyte-macrophage colony-stimulating factor, many studies have shown various anti …

The cytokine IL-10 is a key anti-inflammatory mediator ensuring protection of a host from
over-exuberant responses to pathogens and microbiota, while playing important roles in …

The three cytokines IL-12, IL-10, and IFN-γ have important and cross-regulatory roles in
infection. In the past year, much progress has been made in the understanding of the …

Abstract Interleukin (IL)-10 is considered a prototypical anti-inflammatory cytokine, which
significantly contributes to the maintenance and reestablishment of immune homeostasis …