Premelanosomes are presumed to be essential for melanogenesis in melanocytes and pre-
natal retinal pigment epithelium (RPE) cells. We analysed melanin synthesis in adenoviral …

During a long-term study, a rat exposed to half-amplitude band pass fluorescent blue light
(434 to 475 nm) and receiving a calcium channel blocker developed an ocular mass. By …

Melanin or an associated product in the retinal pigment epithelium (RPE) regulates retinal
maturation, because in albino mammals the central retina is underdeveloped and there is a …

The authors examined spectrophotometrically the ability of drugs to bind with ocular acid-
insoluble melanin. Each drug, at 5 X 10 (-5) M, was incubated at 37 degrees C for 8 hr with 4 …

Melanosomes in retinal tissues of a human, monkey and rat were analyzed by EDX in the
TEM. Samples were prepared by ultramicrotomy at different thicknesses. The material was …

The development of naphthalene cataracts was studied in 5 strains of rattus norvegicus of
different pigmentation. Whereas all animals of the pigmented strains (E3, BDE, DA) …

Intraocular melanoma in the rat Page 1 Laboratory Animals (1978) 12,249-252 Intraocular
melanoma in the rat G. MAGNUSSON, S. MAJEED & JM OFFER Department of Pathology …

Concentration of melanosomes in various tissues has been unknown because of the
impracticability of their direct quantification. Using an indirect approach comprising the …

Choroidal melanocytes differentiate and cease to divide early in postnatal life. They have
characteristic organelles, the melanosomes, which are formed from tyrosine in a reaction …

Energy-filtered analytical transmission electron microscopy was used to image the
ultrastructure and determine quantitatively the chemical composition of pigment granules of …