The substrate specificities and physiological function of the Toxoplasma gondii apicoplast phosphate translocator

HR Johnsen - 2009 - munin.uit.no
The apicomplexan parasites including the causative agents of malaria (Plasmodium spp.)
and toxoplasmosis (Toxoplasma gondii) are running the risk of developing resistance to …

[HTML][HTML] The phosphate translocator is the source of carbon and energy for the Toxoplasma apicoplast and essential for parasite survival

CF Brooks, H Johnsen, GG van Dooren… - Cell host & …, 2010 - ncbi.nlm.nih.gov
Apicomplexa are unicellular eukaryotic pathogens and cause important diseases including
malaria and toxoplasmosis. The discovery of an algal endosymbiont, the apicoplast …

Expression for the phosphate translocator from Toxoplasma gondii in Escherichia coli and purification of the recombinant protein

M Jevtic - 2017 - munin.uit.no
Plastids are plant specific cell organelles, which perform many specialized and essential
functions. Integration of plastids into cellular metabolism requires an extensive exchange of …

Targeting of a transporter to the outer apicoplast membrane in the human malaria parasite Plasmodium falciparum.

LLT Lim LiTing, CP Sayers, CD Goodman… - 2016 - cabidigitallibrary.org
Apicoplasts are vestigial plastids in apicomplexan parasites like Plasmodium, the causative
agent of malaria. Apicomplexan parasites are dependant on their apicoplasts for synthesis …

Targeting of a Transporter to the Outer Apicoplast Membrane in the Human Malaria Parasite Plasmodium falciparum

L Lim, CP Sayers, CD Goodman, GI McFadden - PloS one, 2016 - journals.plos.org
Apicoplasts are vestigial plastids in apicomplexan parasites like Plasmodium, the causative
agent of malaria. Apicomplexan parasites are dependant on their apicoplasts for synthesis …

Cell cycle‐regulated vesicular trafficking of Toxoplasma APT1, a protein localized to multiple apicoplast membranes

A Karnataki, A DeRocher, I Coppens… - Molecular …, 2007 - Wiley Online Library
The apicoplast is a relict plastid essential for viability of the apicomplexan parasites
Toxoplasma and Plasmodium. It is surrounded by multiple membranes that proteins …

A Coccidia-Specific Phosphate Transporter Is Essential for the Growth of Toxoplasma gondii Parasites

J Cui, X Yang, J Yang, R Jia, Y Feng… - Microbiology …, 2022 - Am Soc Microbiol
Toxoplasma gondii is an obligate intracellular parasite that acquires all necessary nutrients
from the hosts, but the exact nutrient acquisition mechanisms are poorly understood. Here …

Carbohydrate Metabolism in the Toxoplasma gondii Apicoplast: Localization of Three Glycolytic Isoenzymes, the Single Pyruvate Dehydrogenase Complex, and a …

T Fleige, K Fischer, DJP Ferguson, UWE Gross… - Eukaryotic …, 2007 - Am Soc Microbiol
Many apicomplexan parasites, such as Toxoplasma gondii and Plasmodium species,
possess a nonphotosynthetic plastid, referred to as the apicoplast, which is essential for the …

[PDF][PDF] The Toxoplasma apicoplast phosphate translocator links cytosolic and apicoplast metabolism and is essential for parasite survival

CF Brooks, H Johnsen, GG van Dooren, M Muthalagi… - Cell host & …, 2010 - cell.com
Apicomplexa are unicellular eukaryotic pathogens that carry a vestigial algal endosymbiont,
the apicoplast. The physiological function of the apicoplast and its integration into parasite …

N-terminal positively charged amino acids, but not their exact position, are important for apicoplast transit peptide fidelity in Toxoplasma gondii

CJ Tonkin, DS Roos, GI McFadden - Molecular and biochemical …, 2006 - Elsevier
The non-photosynthetic plastid–or apicoplast–of Toxoplasma gondii and other
apicomplexan parasites is an essential organelle and promising drug target. Most apicoplast …