Adaptation of prefrontal cortical firing patterns and their fidelity to changes in action–reward contingencies

WJ Kargo, B Szatmary, DA Nitz - Journal of Neuroscience, 2007 - Soc Neuroscience
Animals adapt action-selection policies when the relationship between possible actions and
associated outcomes changes. Prefrontal cortical neurons vary their discharge patterns …

Operant conditioning of primate prefrontal neurons

S Kobayashi, W Schultz… - Journal of …, 2010 - journals.physiology.org
An operant is a behavioral act that has an impact on the environment to produce an
outcome, constituting an important component of voluntary behavior. Because the …

Representation of behavioral tactics and tactics-action transformation in the primate medial prefrontal cortex

Y Matsuzaka, J Tanji, H Mushiake - Journal of Neuroscience, 2016 - Soc Neuroscience
To expedite the selection of action under a structured behavioral context, we develop an
expedient to promote its efficiency: tactics for action selection. Setting up a behavioral …

Context-dependent representation of response-outcome in monkey prefrontal neurons

S Tsujimoto, T Sawaguchi - Cerebral Cortex, 2005 - academic.oup.com
For behaviour to be purposeful, it is important to monitor the preceding behavioural context,
particularly for factors regarding stimulus, response and outcome. The dorsolateral …

[HTML][HTML] Monitoring and updating of action selection for goal-directed behavior through the striatal direct and indirect pathways

S Nonomura, K Nishizawa, Y Sakai, Y Kawaguchi… - Neuron, 2018 - cell.com
The basal ganglia play key roles in adaptive behaviors guided by reward and punishment.
However, despite accumulating knowledge, few studies have tested how heterogeneous …

[HTML][HTML] Prefrontal regulation of behavioural control: evidence from learning theory and translational approaches in rodents

KM Turner, SL Parkes - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Everyday activities require adaptive decision-making and control over our actions to achieve
our goals. Sub-regions within the cortex are widely reported to regulate these choices. Here …

Anterior prefrontal cortex contributes to action selection through tracking of recent reward trends

CK Kovach, ND Daw, D Rudrauf, D Tranel… - Journal of …, 2012 - Soc Neuroscience
The functions of prefrontal cortex remain enigmatic, especially for its anterior sectors,
putatively ranging from planning to self-initiated behavior, social cognition, task switching …

Action-outcome relationships are represented differently by medial prefrontal and orbitofrontal cortex neurons during action execution

NW Simon, J Wood… - Journal of …, 2015 - journals.physiology.org
Internal representations of action-outcome relationships are necessary for flexible
adaptation of motivated behavior in dynamic environments. Prefrontal cortex (PFC) is …

Differentiating neural systems mediating the acquisition vs. expression of goal‐directed and habitual behavioral control

M Liljeholm, S Dunne… - European Journal of …, 2015 - Wiley Online Library
Considerable behavioral data indicate that operant actions can become habitual, as
demonstrated by insensitivity to changes in the action–outcome contingency and in …

Adaptive encoding of outcome prediction by prefrontal cortex ensembles supports behavioral flexibility

A Del Arco, J Park, J Wood, Y Kim… - Journal of …, 2017 - Soc Neuroscience
The prefrontal cortex (PFC) is thought to play a critical role in behavioral flexibility by
monitoring action–outcome contingencies. How PFC ensembles represent shifts in behavior …