Variability in the subcellular distribution of ion channels increases neuronal diversity
Z Nusser - Trends in neurosciences, 2009 - cell.com
The exact location of an ion channel on the axo-somato-dendritic surface of a nerve cell
crucially affects its functional impact. Recent high-resolution immunolocalization …
crucially affects its functional impact. Recent high-resolution immunolocalization …
Differential subcellular distribution of ion channels and the diversity of neuronal function
Z Nusser - Current opinion in neurobiology, 2012 - Elsevier
Following the astonishing molecular diversity of voltage-gated ion channels that was
revealed in the past few decades, the ion channel repertoire expressed by neurons has …
revealed in the past few decades, the ion channel repertoire expressed by neurons has …
Polarized and compartment-dependent distribution of HCN1 in pyramidal cell dendrites
A Lörincz, T Notomi, G Tamás, R Shigemoto… - Nature …, 2002 - nature.com
An ion channel's function depends largely on its location and density on neurons. Here we
used high-resolution immunolocalization to determine the subcellular distribution of the …
used high-resolution immunolocalization to determine the subcellular distribution of the …
Localization and targeting of voltage-dependent ion channels in mammalian central neurons
H Vacher, DP Mohapatra… - Physiological …, 2008 - journals.physiology.org
The intrinsic electrical properties and the synaptic input-output relationships of neurons are
governed by the action of voltage-dependent ion channels. The localization of specific …
governed by the action of voltage-dependent ion channels. The localization of specific …
The distribution and targeting of neuronal voltage-gated ion channels
HC Lai, LY Jan - Nature Reviews Neuroscience, 2006 - nature.com
Voltage-gated ion channels have to be at the right place in the right number to endow
individual neurons with their specific character. Their biophysical properties together with …
individual neurons with their specific character. Their biophysical properties together with …
Organisation of potassium channels on the neuronal surface
R Luján - Journal of chemical neuroanatomy, 2010 - Elsevier
Potassium channels are a family of ion channels that govern the intrinsic electrical
properties of neurons in the brain. Molecular cloning has revealed over 100 genes encoding …
properties of neurons in the brain. Molecular cloning has revealed over 100 genes encoding …
Intrinsic and extrinsic determinants of ion channel localization in neurons
KL Hedstrom, MN Rasband - Journal of neurochemistry, 2006 - Wiley Online Library
Neurons are an extremely diverse group of excitable cells with a wide variety of
morphologies including complex dendritic trees and very long axons. The electrical …
morphologies including complex dendritic trees and very long axons. The electrical …
Homeostasis of functional maps in active dendrites emerges in the absence of individual channelostasis
RK Rathour, R Narayanan - Proceedings of the National …, 2014 - National Acad Sciences
The maintenance of ion channel homeostasis, or channelostasis, is a complex puzzle in
neurons with extensive dendritic arborization, encompassing a combinatorial diversity of …
neurons with extensive dendritic arborization, encompassing a combinatorial diversity of …
Subcellular localization of K+ channels in mammalian brain neurons: remarkable precision in the midst of extraordinary complexity
JS Trimmer - Neuron, 2015 - cell.com
Potassium channels (KChs) are the most diverse ion channels, in part due to extensive
combinatorial assembly of a large number of principal and auxiliary subunits into an …
combinatorial assembly of a large number of principal and auxiliary subunits into an …
Spatial compartmentalization and functional impact of conductance in pyramidal neurons
SR Williams - Nature neuroscience, 2004 - nature.com
Dendritic spikes signal synaptic integration at remote apical dendritic sites in neocortical
pyramidal neurons in vitro. Do dendritic spikes have a salient signaling role under in vivo …
pyramidal neurons in vitro. Do dendritic spikes have a salient signaling role under in vivo …
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