Epigenetic transgenerational actions of environmental factors in disease etiology

MK Skinner, M Manikkam… - Trends in Endocrinology & …, 2010 - cell.com
The ability of environmental factors to promote a phenotype or disease state not only in the
individual exposed but also in subsequent progeny for successive generations is termed …

Endocrine disruptor induction of epigenetic transgenerational inheritance of disease

MK Skinner - Molecular and cellular endocrinology, 2014 - Elsevier
Environmental exposures such as toxicants, nutrition and stress have been shown to
promote the epigenetic transgenerational inheritance of disease susceptibility. Endocrine …

Environmentally induced epigenetic transgenerational inheritance of phenotype and disease

C Guerrero-Bosagna, MK Skinner - Molecular and cellular endocrinology, 2012 - Elsevier
Environmental epigenetics has an important role in regulating phenotype formation or
disease etiology. The ability of environmental factors and exposures early in life to alter …

Environmentally induced epigenetic transgenerational inheritance of disease susceptibility

EE Nilsson, MK Skinner - Translational Research, 2015 - Elsevier
Environmental insults, such as exposure to toxicants or nutritional abnormalities, can lead to
epigenetic changes that are in turn related to increased susceptibility to disease. The focus …

Environmental signals and transgenerational epigenetics

MK Skinner, C Guerrero-Bosagna - Epigenomics, 2009 - Taylor & Francis
The ability of an environmental factor or toxicant to promote a phenotype or disease state not
only in the individual exposed, but also in subsequent progeny for multiple generations, is …

Environmentally induced epigenetic transgenerational inheritance of disease

EE Nilsson, I Sadler-Riggleman… - Environmental …, 2018 - academic.oup.com
Ancestral environmental exposures such as toxicants, abnormal nutrition or stress can
promote the epigenetic transgenerational inheritance of disease and phenotypic variation …

Epigenetic transgenerational actions of endocrine disruptors

MK Skinner, M Manikkam, C Guerrero-Bosagna - Reproductive toxicology, 2011 - Elsevier
Environmental factors have a significant impact on biology. Therefore, environmental
toxicants through similar mechanisms can modulate biological systems to influence …

Elusive inheritance: transgenerational effects and epigenetic inheritance in human environmental disease

SN Martos, W Tang, Z Wang - Progress in biophysics and molecular …, 2015 - Elsevier
Epigenetic mechanisms involving DNA methylation, histone modification, histone variants
and nucleosome positioning, and noncoding RNAs regulate cell-, tissue-, and …

Intergenerational transmission of programmed effects: public health consequences

AJ Drake, L Liu - Trends in Endocrinology & Metabolism, 2010 - cell.com
Epidemiological studies have shown that the environment experienced in early life can
'programme'susceptibility to later disease. Furthermore, there is increasing evidence that …

Environmentally induced epigenetic transgenerational inheritance of reproductive disease

EE Nilsson, MK Skinner - Biology of Reproduction, 2015 - academic.oup.com
Reproductive disease and fertility issues have dramatically increased in the human
population over the last several decades, suggesting environmental impacts. Epigenetics …