Stroke is a leading cause of disability worldwide and hence remains a major medical
concern. Besides several pathological features, such as excitotoxicity, peri-infarct …

Ischemic stroke accounts for the majority of stroke cases and constitutes a major cause of
death and disability in the industrialized world. Inflammation has been reported to constitute …

Historically, the brain has been considered an immune-privileged organ separated from the
peripheral immune system by the blood–brain barrier. However, immune responses do …

The immune response to ischemic stroke is an area of study that is at the forefront of stroke
research and presents promising new avenues for treatment development. Upon cerebral …

After ischemic stroke, the integrity of the blood-brain barrier is compromised. Peripheral
immune cells, including neutrophils, T cells, B cells, dendritic cells, and macrophages …

Ischemic stroke is a leading cause of disability and mortality. Despite extensive efforts in
stroke research, the only pharmacological treatment currently available is arterial …

Aims Ischemic stroke is one of the leading causes of death worldwide and the most common
cause of disability in Western countries. Multiple mechanisms contribute to the development …

Stroke, in association with its complications, is one of the leading causes of mortality and
morbidity worldwide. Cerebral ischemia triggers an inflammatory response in the brain that …

Background The brain's initial innate response to stroke is primarily mediated by microglia,
the resident macrophage of the CNS. However, as early as 4 h after stroke, the blood–brain …

Ischemic stroke, which accounts for 75–80% of all strokes, is the predominant cause of
morbidity and mortality worldwide. The post-stroke immune response has recently emerged …