The interplay between adipose tissue and skeletal muscle and the impact on mobility and
aging remain enigmatic. The progressive decline in mobility promoted by aging has been …

Advancing age is associated with progressive declines in physiological function that lead to
overt chronic disease, frailty, and eventual mortality. Importantly, age-related physiological …

Sarcopenia is a universal characteristic of the aging process and is often accompanied by
increases in whole-body adiposity. These changes in body composition have important …

A growing body of scientific literature suggests that not only changes in skeletal muscle
mass, but also other factors underpinning muscle quality, play a role in the decline in …

Adipose tissue has a variety of diverse functions that maintain energy homeostasis. In
conditions of excess energy availability, adipose tissue increases its lipid storage and …

Key points Ageing is associated with increased systemic inflammation and metabolic
dysfunction that contributes to the development of age‐associated diseases. The role of …

Adipose tissue, which is the crucial energy reservoir and endocrine organ for the
maintenance of systemic glucose, lipid, and energy homeostasis, undergoes significant …

Sarcopenia is of important clinical relevance for loss of independence in older adults. The
prevalence of obesity in combination with sarcopenia ('sarcopenic-obesity') is increasing at …

Muscle's structural composition is an important factor underlying muscle strength and
physical function in older adults. There is an increasing amount of research to support the …

Sarcopenic obesity is becoming a global health concern, owing to the rising older
population, causing cardiometabolic morbidity and mortality. Loss of muscle exceeding …