Molecular targets and anticancer potential of sanguinarine—A benzophenanthridine alkaloid
Background Cancer is an enormous global health burden, and should be effectively
addressed with better therapeutic strategies. Currently, over 60% of the clinically approved …
addressed with better therapeutic strategies. Currently, over 60% of the clinically approved …
Anticancer potential of sanguinarine for various human malignancies
Sanguinarine (Sang)–a benzophenanthridine alkaloid extracted from Sanguinaria
canadensis–exhibits antioxidant, anti-inflammatory, proapoptotic and growth inhibitory …
canadensis–exhibits antioxidant, anti-inflammatory, proapoptotic and growth inhibitory …
[HTML][HTML] Antitumor effects of the benzophenanthridine alkaloid sanguinarine: Evidence and perspectives
R Gaziano, G Moroni, C Buè, MT Miele… - World Journal of …, 2016 - ncbi.nlm.nih.gov
Historically, natural products have represented a significant source of anticancer agents,
with plant-derived drugs becoming increasingly explored. In particular, sanguinarine is a …
with plant-derived drugs becoming increasingly explored. In particular, sanguinarine is a …
Molecular mechanisms of Sanguinarine in cancer prevention and treatment
Historically, natural plant-derived drugs received a great impact of consideration in the
treatment of several human-associated disorders. Cancer is a devastating disease and the …
treatment of several human-associated disorders. Cancer is a devastating disease and the …
[HTML][HTML] Bioactivity and mechanism of action of sanguinarine and its derivatives in the past 10 years
LJ Huang, JX Lan, JH Wang, H Huang, K Lu… - Biomedicine & …, 2024 - Elsevier
Sanguinarine is a quaternary ammonium benzophenanthine alkaloid found in traditional
herbs such as Chelidonium, Corydalis, Sanguinarum, and Borovula. It has been proven to …
herbs such as Chelidonium, Corydalis, Sanguinarum, and Borovula. It has been proven to …
Antitumour activities of sanguinarine and related alkaloids
I Slaninová, K Pěnčíková, J Urbanová, J Slanina… - Phytochemistry …, 2014 - Springer
Sanguinarine is a best-known member of a relatively small group of quaternary benzo [c]
phenanthridine alkaloids (QBAs). QBAs are widely distributed in the family Papaveraceae …
phenanthridine alkaloids (QBAs). QBAs are widely distributed in the family Papaveraceae …
Sanguinarine inhibits growth of human cervical cancer cells through the induction of apoptosis
JY Xu, QH Meng, Y Chong, Y Jiao… - Oncology …, 2012 - spandidos-publications.com
Sanguinarine, a natural benzophenanthridine alkaloid, has been shown to possess
anticancer activity in vitro and in vivo. In the present study, we demonstrated that …
anticancer activity in vitro and in vivo. In the present study, we demonstrated that …
Sanguinarine inhibits the proliferation of BGC-823 gastric cancer cells via regulating miR-96-5p/miR-29c-3p and the MAPK/JNK signaling pathway
XZ Dong, Y Song, YP Lu, Y Hu, P Liu… - Journal of natural …, 2019 - Springer
Sanguinarine (SAN), a quaternary benzophenanthridine alkaloid extracted from the root of
Papaveraceae plants, has shown antitumour effects in multiple cancer cells. However, the …
Papaveraceae plants, has shown antitumour effects in multiple cancer cells. However, the …
Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through …
MH Han, SO Kim, GY Kim, TK Kwon, BT Choi… - Anti-cancer …, 2007 - journals.lww.com
Sanguinarine is a benzophenanthridine alkaloid that is derived from the root of Sanguinaria
canadensis and other poppy fumaria species, and is known to have antimicrobial …
canadensis and other poppy fumaria species, and is known to have antimicrobial …
Sanguinarine and its role in chronic diseases
The use of natural products derived from plants as medicines precedes even the recorded
human history. In the past few years there were renewed interests in developing natural …
human history. In the past few years there were renewed interests in developing natural …