While immunotherapy has had an important impact on cancer treatment, only approximately
a quarter of patients respond to these treatments. Why does it work in some patients but not …

Cancer immunotherapy is demonstrating impressive clinical benefit in different malignancies
and clinical oncologists are increasingly turning their attention to immune-oncology. It is now …

Cancer greatly affects the quality of life of humans worldwide and the number of patients
suffering from it is continuously increasing. Over the last century, numerous treatments have …

The immune system has an intricate and complex relationship with tumorigenesis; while it
has the capacity to identify and eliminate cancerous cells, the emergence of a tumor …

In recent years, cancer immunotherapy research has made remarkable progress, completely
transforming the cancer treatment landscape. In 2021, we proudly introduced the Special …

Simple Summary The cancer-immunity cycle is characterized by various stimulatory and
inhibitory factors, which together regulate the immune response and halt the extreme …

Within the past two decades, researchers and physicians have witnessed the most
impressive flourishing of studies aimed at understanding how the immune system interacts …

Immunotherapy strategies against cancer are emerging as powerful weapons for treatment
of this disease. The success of checkpoint inhibitors against metastatic melanoma and …

Tumor cells often evoke specific immune responses that, however, fail to eliminate all the
tumor cells. The development of cancer immunotherapies is, therefore, mostly focused on …

Interplay among immune activation and cancer pathogenesis provides the framework for a
novel subspecialty known as immunooncology. In the rapidly evolving field of …