Aquaporins in renal diseases

J He, B Yang - International journal of molecular sciences, 2019 - mdpi.com
Aquaporins (AQPs) are a family of highly selective transmembrane channels that mainly
transport water across the cell and some facilitate low-molecular-weight solutes. Eight AQPs …

Localization and trafficking of aquaporin 2 in the kidney

K Takata, T Matsuzaki, Y Tajika, A Ablimit… - Histochemistry and cell …, 2008 - Springer
Aquaporins (AQPs) are membrane proteins serving in the transfer of water and small solutes
across cellular membranes. AQPs play a variety of roles in the body such as urine formation …

Aquaporins in the kidney: physiology and pathophysiology

W Su, R Cao, X Zhang, Y Guan - American Journal of …, 2020 - journals.physiology.org
The kidney is the central organ involved in maintaining water and sodium balance. In human
kidneys, nine aquaporins (AQPs), including AQP1–8 and AQP11, have been found and are …

Aquaporins: The renal water channels

SK Agarwal, A Gupta - Indian Journal of Nephrology, 2008 - journals.lww.com
Water is the most abundant molecule in any cell. Specialized membrane channel, proteins
called aquaporins, facilitate water transport across cell membranes. At least seven …

Aquaporins in the kidney: from molecules to medicine

S Nielsen, J Frøkiær, D Marples… - Physiological …, 2002 - journals.physiology.org
The discovery of aquaporin-1 (AQP1) answered the long-standing biophysical question of
how water specifically crosses biological membranes. In the kidney, at least seven …

Aquaporins in urinary system

Y Li, W Wang, T Jiang, B Yang - Aquaporins, 2017 - Springer
Several aquaporin (AQP)-type water channels are expressed in kidney: AQP1 in the
proximal tubule, thin descending limb of Henle, and vasa recta; AQP2-6 in the collecting …

Molecular biology of aquaporins

C Li, W Wang - Aquaporins, 2017 - Springer
Aquaporins (AQPs) are a family of membrane water channels that basically function as
regulators of intracellular and intercellular water flow. To date, thirteen AQPs, which are …

Aquaporins in kidney pathophysiology

Y Noda, E Sohara, E Ohta, S Sasaki - Nature Reviews Nephrology, 2010 - nature.com
Seven aquaporin water channels are expressed in human kidneys, and they have key roles
in maintaining body water homeostasis. Impairment of their function can result in …

Aquaporins: a promising target for drug development

K Jeyaseelan, S Sepramaniam… - Expert opinion on …, 2006 - Taylor & Francis
Aquaporins (AQPs) are a family of small hydrophobic, integral membrane proteins that are
expressed in all living organisms and play critical roles in controlling the water flow into and …

Physiology and pathophysiology of renal aquaporins

TH Kwon, H Hager, LN Nejsum… - Seminars in …, 2001 - seminarsinnephrology.org
The discovery of aquaporin-1 (AQP1) by Agre and associates answered the longstanding
biophysical question of how water specifically crosses biological membranes. In the kidney …