Qiliqiangxin improves cardiac function and attenuates cardiac remodelling in doxorubicin-induced heart failure rats

X Sun, G Chen, Y Xie, D Jiang, J Han… - Pharmaceutical …, 2020 - Taylor & Francis
Context Therapeutic doxorubicin administration is restricted as this anticancer drug may be
cardiotoxic. The traditional Chinese medicine qiliqiangxin has been approved for clinical …

[HTML][HTML] Qiliqiangxin attenuates cardiac remodeling via inhibition of TGF-β1/Smad3 and NF-κB signaling pathways in a rat model of myocardial infarction

A Han, Y Lu, Q Zheng, J Zhang, YZ Zhao… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Qiliqiangxin (QL), a traditional Chinese medicine, has been
demonstrated to be effective and safe for the treatment of chronic heart failure. Left …

[HTML][HTML] Qiliqiangxin improves cardiac function and attenuates cardiac remodeling in rats with experimental myocardial infarction

J Wang, J Zhou, X Ding, L Zhu, K Jiang… - … Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Objective: It has been reported that Qiliqiangxin (QL), a traditional Chinese medicine
compound, could inhibit cardiac hypertrophy and remodeling, and improve cardiac function …

[HTML][HTML] Traditional Chinese Medication Qiliqiangxin attenuates cardiac remodeling after acute myocardial infarction in mice

L Tao, S Shen, S Fu, H Fang, X Wang, S Das… - Scientific Reports, 2015 - nature.com
In a multicenter randomized double-blind study we demonstrated that Qiliqiangxin (QLQX), a
traditional Chinese medicine, had a protective effect in heart failure patients. However …

Protective effect of Qiliqiangxin against Doxorubicin‐induced cardiomyopathy by suppressing excessive autophagy and apoptosis

Y Qin, C Lv, X Zhang, W Ruan, X Xu… - Cardiovascular …, 2022 - Wiley Online Library
Background. Doxorubicin (DOX) is one of the most potent and widely prescribed antitumor
agents; however, its clinical use is limited by cardiac side effects. In this study, we aimed to …

[HTML][HTML] Traditional Chinese medication Qiliqiangxin protects against cardiac remodeling and dysfunction in spontaneously hypertensive rats

H Wang, X Zhang, P Yu, Q Zhou, J Zhang… - … Journal of Medical …, 2017 - ncbi.nlm.nih.gov
Qiliqiangxin (QLQX), a traditional Chinese herbs medication, exerted protective effect in
chronic heart failure patients in a multicenter randomized double-blind study. QLQX has also …

[HTML][HTML] Qiliqiangxin attenuates isoproterenol-induced cardiac remodeling in mice

J Zhang, M Huang, S Shen, X Wu, X Wu… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Background: To further explore the role of PPARγ in QL treatment, ISO-induced mice model
and following methods were established. Methods: Cardiac remodeling on mice model was …

[HTML][HTML] Qiliqiangxin protects against cardiac ischemia-reperfusion injury via activation of the mTOR pathway

Y Zhou, H Fang, S Lin, S Shen, L Tao, J Xiao… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: Qiliqiangxin (QL) has been used for the treatment of chronic heart failure
in China. Accumulating evidence suggests QL's cardio-protective effects on continuous …

[PDF][PDF] Qiliqiangxin capsule improves cardiac remodeling in rats with DOCA-salt-induced diastolic dysfunction.

JM Hao, P Sun, Y Zeng, H Zhang… - European Review for …, 2023 - europeanreview.org
OBJECTIVE: The aim of this study was to investigate the protective effect and mechanism of
action (MOA) of Qiliqiangxin capsule (QL) in the deoxycorticosterone acetate (DOCA) salt …

Qiliqiangxin Improves Cardiac Function through Regulating Energy Metabolism via HIF‐1α‐Dependent and Independent Mechanisms in Heart Failure Rats after …

Y Wang, M Fu, J Wang, J Zhang, X Han… - BioMed research …, 2020 - Wiley Online Library
The present study is aimed at investigating whether Qiliqiangxin (QL) could regulate
myocardial energy metabolism in heart failure rats after acute myocardial infarction (AMI) …