[HTML][HTML] RNA-binding proteins as important regulators of long non-coding RNAs in cancer

K Jonas, GA Calin, M Pichler - International journal of molecular sciences, 2020 - mdpi.com
The majority of the genome is transcribed into pieces of non-(protein) coding RNA, among
which long non-coding RNAs (lncRNAs) constitute a large group of particularly versatile …

New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer

ZT Yao, YM Yang, MM Sun, Y He, L Liao… - Cancer …, 2022 - Wiley Online Library
With the development of proteomics and epigenetics, a large number of RNA‐binding
proteins (RBPs) have been discovered in recent years, and the interaction between long …

[HTML][HTML] Long non-coding RNA and RNA-binding protein interactions in cancer: experimental and machine learning approaches

H Shaath, R Vishnubalaji, R Elango… - Seminars in cancer …, 2022 - Elsevier
Understanding the complex and specific roles played by non-coding RNAs (ncRNAs), which
comprise the bulk of the genome, is important for understanding virtually every hallmark of …

The long (lncRNA) and short (miRNA) of it: TGFβ-mediated control of RNA-binding proteins and noncoding RNAs

H Janakiraman, RP House, VK Gangaraju… - Molecular Cancer …, 2018 - AACR
RNA-binding proteins (RBP) and noncoding RNAs (ncRNA), such as long noncoding RNAs
(lncRNA) and microRNAs (miRNA), control co-and posttranscriptional gene regulation …

RNA-binding proteins: Underestimated contributors in tumorigenesis

Y Zhao, C Mir, Y Garcia-Mayea, R Paciucci… - Seminars in Cancer …, 2022 - Elsevier
Abstract mRNA export, translation, splicing, cleavage or capping determine mRNA stability,
which represents one of the primary aspects regulating gene expression and function. RNA …

Cancer the 'RBP'eutics–RNA-binding proteins as therapeutic targets for cancer

S Mohibi, X Chen, J Zhang - Pharmacology & therapeutics, 2019 - Elsevier
RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …

[HTML][HTML] RNA-binding proteins in cancer: functional and therapeutic perspectives

D Kang, Y Lee, JS Lee - Cancers, 2020 - mdpi.com
Simple Summary RNA-binding proteins (RBPs) play central roles in regulating
posttranscriptional expression of genes. Many of them are known to be deregulated in a …

Cooperation and competition by RNA-binding proteins in cancer

S Nag, B Goswami, SD Mandal, PS Ray - Seminars in Cancer Biology, 2022 - Elsevier
Post-transcriptional regulation of gene expression plays a major role in determining the
cellular proteome in health and disease. Post-transcriptional control mechanisms are …

RNA-binding proteins and cancer metastasis

S Wang, Z Sun, Z Lei, HT Zhang - Seminars in cancer biology, 2022 - Elsevier
RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …

Diverse roles of RNA‐binding proteins in cancer traits and their implications in gastrointestinal cancers

K Masuda, Y Kuwano - Wiley Interdisciplinary Reviews: RNA, 2019 - Wiley Online Library
Gene expression patterns in cancer cells are strongly influenced by posttranscriptional
mechanisms. RNA‐binding proteins (RBPs) play key roles in posttranscriptional gene …