Loss of TAB3 expression by shRNA exhibits suppressive bioactivity and increased chemical sensitivity of ovarian cancer cell lines via the NF‐κB pathway
Y Chen, X Wang, C Duan, J Chen, M Su, Y Jin… - Cell …, 2016 - Wiley Online Library
Ovarian cancer is a leading cause of death among gynaecologic malignancies. Despite
many years of research, it still remains sparing in reliable diagnostic markers and methods …
many years of research, it still remains sparing in reliable diagnostic markers and methods …
[HTML][HTML] TAB3 promotes human esophageal squamous cell carcinoma proliferation and invasion via the NF‑κB pathway
J Zhao, L Gai, Y Gao, W Xia, D Shen… - Oncology …, 2018 - spandidos-publications.com
Esophageal squamous cell carcinoma (ESCC) has become one of the most common
causes of cancer‑associated mortality worldwide. Transforming growth factor‑activated …
causes of cancer‑associated mortality worldwide. Transforming growth factor‑activated …
TAB3 overexpression promotes cell proliferation in non-small cell lung cancer and mediates chemoresistance to CDDP in A549 cells via the NF-κB pathway
J Chen, J Gu, J Feng, Y Liu, Q Xue, T Ni, Z Wang, L Jia… - Tumor Biology, 2016 - Springer
Transforming growth factor-activated kinase 1 (TAK1)-binding protein 3 (TAB3) is essential
for the activation of the nuclear factor kappa B (NF-κB) pathway and has important roles in …
for the activation of the nuclear factor kappa B (NF-κB) pathway and has important roles in …
[HTML][HTML] Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling
PCH Cai, L Shi, VWS Liu, HWM Tang, IJ Liu… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Transforming growth factor (TGF)-β-activating kinase 1 (TAK1) is a serine/threonine kinase
which is frequently associated with human cancer progression. However, its functional role …
which is frequently associated with human cancer progression. However, its functional role …
Inhibition of ovarian cancer cell growth by a novel TAK1 inhibitor LYTAK1
L Ying, Y Chunxia, L Wei - Cancer chemotherapy and pharmacology, 2015 - Springer
Purpose Transforming growth factor-β-activating kinase 1 (TAK1) has been implicated in
promoting ovarian cancer progression. Here, we evaluated the anti-ovarian cancer effect of …
promoting ovarian cancer progression. Here, we evaluated the anti-ovarian cancer effect of …
Altered TAB1: IκB kinase interaction promotes transforming growth factor β–mediated nuclear factor-κB activation during breast cancer progression
JR Neil, WP Schiemann - Cancer research, 2008 - AACR
The conversion of transforming growth factor β (TGF-β) from a tumor suppressor to a tumor
promoter occurs frequently during mammary tumorigenesis, yet the molecular mechanisms …
promoter occurs frequently during mammary tumorigenesis, yet the molecular mechanisms …
TAB2 promotes the biological functions of head and neck squamous cell carcinoma cells via EMT and PI3K pathway
H Liu, H Zhang, H Fan, S Tang, J Weng - Disease Markers, 2022 - Wiley Online Library
Background. Transforming growth factor β1‐activated kinase 1 binding protein 2 (TAB2)
mediates a variety of biological processes through activated nuclear factor κ‐light‐chain …
mediates a variety of biological processes through activated nuclear factor κ‐light‐chain …
[HTML][HTML] A novel functional domain of Tab2 involved in the interaction with estrogen receptor alpha in breast cancer cells
S Reineri, S Agati, V Miano, M Sani, P Berchialla… - Plos one, 2016 - journals.plos.org
Tab2, originally described as a component of the inflammatory pathway, has been
implicated in phenomena of gene de-repression in several contexts, due to its ability to …
implicated in phenomena of gene de-repression in several contexts, due to its ability to …
[HTML][HTML] Downregulation of TAB182 promotes cancer stem-like cell properties and therapeutic resistance in triple-negative breast cancer cells
H He, S Wang, W Zhang, S Gao, H Guan, P Zhou - BMC cancer, 2023 - Springer
TAB182 participates in DNA damage repair and radio-/chemosensitivity regulation in
various tumors, but its role in tumorigenesis and therapeutic resistance in breast cancer …
various tumors, but its role in tumorigenesis and therapeutic resistance in breast cancer …
[HTML][HTML] Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-β-activated kinase 1 …
P Singhirunnusorn, S Suzuki, N Kawasaki… - Journal of Biological …, 2005 - ASBMB
Transforming growth factor-β-activated kinase 1 (TAK1) mitogen-activated protein kinase
kinase kinase has been shown to be activated by cellular stresses including tumor necrosis …
kinase kinase has been shown to be activated by cellular stresses including tumor necrosis …