Evolutionarily conserved DDB1‐and CUL4‐associated factor 13 (DCAF13) is a recently
discovered substrate receptor for the cullin RING‐finger ubiquitin ligase 4 (CRL4) E3 …

DDB1 and CUL4 associated factor 13 (DCAF13) is a substrate receptor in the CUL4‐DDB1
E3 ligase, and its expression is associated with the prognosis of certain cancers. In the …

ABSTRACT DCAF13 is firstly identified as a substrate receptor of CUL4-DDB1 E3 ligase
complex. This study disclosed that DCAF13 acted as a novel RNA binding protein (RBP) that …

DDB1 and CUL4 associated factor 13 (DCAF13) is a protein coding gene located on
chromosome 8q22. 3, which is a hotspot amplified in various cancers. DCAF13 has been …

Epithelial-mesenchymal transition (EMT) is an evolutionarily conserved developmental
program that has been implicated in tumorigenesis and confers metastatic properties upon …

DCAF4L2 is a member of WD-repeat proteins, which commonly serve as mediators of
protein-protein interplay. In this study, we reported that elevated DCAF4L2 expression in …

DCAF13 is a substrate recognition protein in the ubiquitin‐proteasome system with
oncogenic effects in several malignant tumors. However, it is unclear that the relationship …

Abstract Deciphering how DCAFs (DDB1‐CUL4 Associated Factors) modulate a broad
spectrum of cellular processes, including cell cycle progression and maintenance of …

Cell cycle progression in mammals is strictly controlled by a number of cyclin-dependent
kinases (CDKs) and CDK inhibitors (CKIs), the expression of which is often dysregulated in …

The CUL4-DDB1 ubiquitin ligase regulates cell proliferation, survival, DNA repair, and
genomic integrity through targeted ubiquitination of key regulators, yet the substrate …