Background: Aspirin-exacerbated respiratory disease (AERD), an asthma phenotype, often
presents with severe manifestations and it remains widely underdiagnosed because of …

We developed a genetic marker set of single nucleotide polymorphisms (SNPs) by summing
risk scores of 14 SNPs showing a significant association with aspirin-exacerbated …

Aspirin exacerbated respiratory disease (AERD) is a condition caused by increased
bronchoconstriction in people with asthma after taking aspirin or another NSAID. Molecular …

Although aspirin-exacerbated respiratory disease (AERD) has attracted a great deal of
attention because of its association with severe asthma, it remains widely under-diagnosed …

Aspirin-exacerbated respiratory disease (AERD) is a nonallergic clinical syndrome
characterized by a severe decline in forced expiratory volume in one second (FEV1) …

The aim of the present study was to develop a diagnostic set of single-nucleotide
polymorphisms (SNPs) for discriminating aspirin-exacerbated respiratory disease (AERD) …

Purpose Endoplasmic reticulum (ER) stress has recently been observed to activate NF-
kappaB and induce inflammatory responses such as asthma. Activating transcription factor …

Aspirin exacerbated respiratory disease (AERD) is a condition caused by increased
bronchoconstriction in people with asthma after taking aspirin or another NSAID. Molecular …

Aspirin exacerbated respiratory disease (AERD) is a set of diseases of the unified airway,
and its physiopathology is related to disruption of the metabolism of arachidonic acid (AA) …

Aspirin can cause bronchoconstriction in a subset of asthmatic patients through largely
unknown mechanism. IL-4 plays a central role in Th2 differentiation and maintenance. In the …