Inflammasomes have emerged as critical innate sensors of host immune that defense
against pathogen infection, metabolism syndrome, cellular stress and cancer metastasis in …

Inflammation contributes to the pathogenesis of most acute and chronic liver diseases.
Inflammasomes are multiprotein complexes that can sense danger signals from damaged …

Inflammasomes are multiprotein complexes that can sense danger signals and activate
caspase-1 to mediate pro-inflammatory cytokines release and pyroptotic cell death. There …

The involvement of inflammasomes in the proinflammatory response observed in chronic
liver diseases, such as alcohol-associated liver disease (ALD) and nonalcoholic fatty liver …

Tissue stress and cell death result in inflammation even in the absence of pathogens. Such
sterile inflammation is dependent on a cytosolic complex of proteins inside immune cells …

Inflammasomes have become an important natural sensor of host immunity, and can protect
various organs against pathogenic infections, metabolic syndromes, cellular stress and …

An inflammatory response consists of two consecutive steps: priming and triggering, to
prepare and activate inflammatory responses, respectively. The cardinal feature of the …

The inflammasome is widely acknowledged for its crucial role in the pathogenesis of
cancers and many neurodegenerative, metabolic, and auto-inflammatory diseases in recent …

Inflammation is a common element in the pathogenesis of most chronic liver diseases that
lead to fibrosis and cirrhosis. Inflammation is characterized by activation of innate immune …

Hepatitis is damage and inflammation of the liver. It is triggered by both environmental and
endogenous insults and is a platform for developing liver cirrhosis and cancer. Both innate …