TAR DNA-binding protein of about 43 kDa (TDP-43) is the main ubiquitinated peptide in tau-
negative frontotemporal lobar degeneration (FTLD). TDP-43 is typically a nuclear protein …

Background Recently, TAR DNA-binding protein 43 (TDP-43) was identified as the major
component of ubiquitin-positive tau-negative neuronal and glial inclusions in the most …

Frontotemporal lobar degeneration (FTLD) with TDP-43-immunoreactive inclusions (FTLD–
TDP) is a neurodegenerative disease associated with clinical, genetic, and …

In 2006, TAR DNA-binding protein 43 (TDP-43), a highly conserved nuclear protein, was
identified as the major disease protein in amyotrophic lateral sclerosis (ALS) and in the most …

TAR DNA-binding protein 43 (TDP-43) is a major pathological protein of sporadic and
familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions …

The rapid confirmation of the initial report by Neumann et al.(Science 314: 130–133, 2006)
that transactive response (TAR)-DNA-binding protein 43 (TDP-43) is the major disease …

Abstract TAR DNA-binding protein (TDP-43) is a major component of most ubiquitin-positive
neuronal and glial inclusions of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar …

Herein, we review advances in understanding a group of disorders collectively known as
TAR-DNA binding protein 43 (TDP-43) proteinopathies since the report that TDP-43 is the …

Abstract Recently, TDP-43, a 43 kDa nuclear TAR DNA-binding protein, was identified as
the major disease protein in frontotemporal lobar degeneration with ubiquitinated inclusions …

Frontotemporal dementia (FTD) causes progressive personality, behavior and/or language
disturbances and represents the second most common form of dementia under the age of …