Two-months-off, four-months-on antiretroviral regimen increases the risk of resistance, compared with continuous therapy: a randomized trial involving West African …
C Danel, R Moh, ML Chaix, D Gabillard… - The Journal of …, 2009 - academic.oup.com
Background. A randomized trial was launched in Côte d'Ivoire in 2002 to compare
continuous antiretroviral treatment (hereafter,“C-ART”) to an ART regimen of 2 months off …
continuous antiretroviral treatment (hereafter,“C-ART”) to an ART regimen of 2 months off …
Varied patterns of HIV-1 drug resistance on failing first-line antiretroviral therapy in South Africa
CL Wallis, JW Mellors, WDF Venter… - JAIDS Journal of …, 2010 - journals.lww.com
Background: The South African national antiretroviral therapy roll-out program is entering its
sixth year, with over 570,000 adults accessing treatment. HIV-1 drug resistance is a potential …
sixth year, with over 570,000 adults accessing treatment. HIV-1 drug resistance is a potential …
Factors associated with first-line antiretroviral therapy failure amongst HIV-infected African patients: a case-control study
Background: Since 2001, anti-retroviral therapy (ART) has been provided to over 75,000 HIV-
infected patients at the USAID-Academic Model Providing Access to Healthcare (AMPATH) …
infected patients at the USAID-Academic Model Providing Access to Healthcare (AMPATH) …
Declining prevalence of HIV-1 drug resistance in antiretroviral treatment-exposed individuals in Western Europe
A De Luca, D Dunn, M Zazzi, R Camacho… - The Journal of …, 2013 - academic.oup.com
HIV-1 drug resistance represents a major obstacle to infection and disease control. This
retrospective study analyzes trends and determinants of resistance in antiretroviral treatment …
retrospective study analyzes trends and determinants of resistance in antiretroviral treatment …
Emerging HIV-1 drug resistance after roll-out of antiretroviral therapy in sub-Saharan Africa
RL Hamers, KCE Sigaloff, C Kityo… - Current Opinion in …, 2013 - journals.lww.com
TDR is on the rise after the recent scale-up of ART in Africa. To prevent the development and
spread of drug resistance and sustain the effectiveness of ART programmes, there is a need …
spread of drug resistance and sustain the effectiveness of ART programmes, there is a need …
Virological failure rates and HIV‐1 drug resistance patterns in patients on first‐line antiretroviral treatment in semirural and rural Gabon
F Liégeois, C Vella, S Eymard‐Duvernay… - Journal of the …, 2012 - Wiley Online Library
Introduction As antiretroviral treatment (ART) continues to expand in resource‐limited
countries, the emergence of HIV drug resistance mutations (DRMs) is challenging in these …
countries, the emergence of HIV drug resistance mutations (DRMs) is challenging in these …
Emergence of multiclass drug–resistance in HIV-2 in antiretroviral-treated individuals in senegal: implications for hiv-2 treatment in resouce-limited West Africa
GS Gottlieb, NMD Badiane, SE Hawes… - Clinical Infectious …, 2009 - academic.oup.com
Background. The efficacy of various antiretroviral (ARV) therapy regimens for human
immunodeficiency virus type 2 (HIV-2) infection remains unclear. HIV-2 is intrinsically …
immunodeficiency virus type 2 (HIV-2) infection remains unclear. HIV-2 is intrinsically …
Scale-up of antiretroviral treatment in sub-Saharan Africa is accompanied by increasing HIV-1 drug resistance mutations in drug-naive patients
AF Aghokeng, C Kouanfack, C Laurent, E Ebong… - Aids, 2011 - journals.lww.com
Objectives: To evaluate the frequency and progression over time of the WHO-defined
transmitted HIV-1 drug resistance mutations (DRMs) among antiretroviral treatment (ART) …
transmitted HIV-1 drug resistance mutations (DRMs) among antiretroviral treatment (ART) …
HIV type-1 clade C resistance genotypes in treatment-naive patients and after first virological failure in a large community antiretroviral therapy programme
Background This study aimed to evaluate HIV type-1 (HIV-1) drug resistance pretreatment
and in those failing first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-based …
and in those failing first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-based …
Virological efficacy and emergence of drug resistance in adults on antiretroviral treatment in rural Tanzania
A Johannessen, E Naman, SL Kivuyo, MJ Kasubi… - BMC infectious …, 2009 - Springer
Background Virological response to antiretroviral treatment (ART) in rural Africa is poorly
described. We examined virological efficacy and emergence of drug resistance in adults …
described. We examined virological efficacy and emergence of drug resistance in adults …