Low-frequency drug resistance in HIV-infected Ugandans on antiretroviral treatment is associated with regimen failure

F Kyeyune, RM Gibson, I Nankya… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Most patients failing antiretroviral treatment in Uganda continue to fail their treatment
regimen even if a dominant drug-resistant HIV-1 genotype is not detected. In a recent …

Evolution of resistance to drugs in HIV-1-infected patients failing antiretroviral therapy

R Kantor, RW Shafer, S Follansbee, J Taylor, D Shilane… - Aids, 2004 - journals.lww.com
Design: A retrospective study of consecutive sequence samples from 106 patients at one
institution with viral load (VL) of more than 400 copies/ml, with no change in ART for more …

Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI‐based regimens in the western cape, South Africa

GU van Zyl, L van der Merwe… - Journal of medical …, 2011 - Wiley Online Library
Antiretroviral drug resistance in patients failing non‐nucleoside reverse transcriptase
inhibitor (NNRTI)‐based first‐line combination antiretroviral treatment (ART) is influenced …

[PDF][PDF] HIV antiretroviral drug resistance in Africa

JN Nkengasong, C Adje-Toure, PJ Weidle - Aids Rev, 2004 - researchgate.net
Highly active antiretroviral therapy (HAART) has dramatically reduced mortality and
morbidity in HIV-infected persons in developed countries. Although the use of HAART …

[HTML][HTML] Virological efficacy and immunological recovery among Ethiopian HIV-1 infected adults and children

A Mulu, UG Liebert, M Maier - BMC infectious diseases, 2014 - Springer
Background Introduction of antiretroviral therapy (ART) in sub-Saharan Africa was a hot
debate due to many concerns about adherence, logistics and resistance. Currently, it has …

Genotypic resistance profiles of HIV-2-treated patients in West Africa

C Charpentier, S Eholié, X Anglaret, M Bertine… - Aids, 2014 - journals.lww.com
Objective: To assess the virological response, genotypic resistance profiles, and
antiretroviral plasma concentrations in HIV-2 antiretroviral-treated (antiretroviral therapy …

Risk of resistance to highly active antiretroviral therapy among HIV-positive injecting drug users: a meta-analysis

D Werb, EJ Mills, JSG Montaner… - The Lancet Infectious …, 2010 - thelancet.com
Although highly active antiretroviral therapy (HAART) is an effective treatment for HIV, many
physicians withhold this treatment from HIV-positive injecting drug users (IDUs) because of …

Detection of HIV drug resistance during antiretroviral treatment and clinical progression in a large European cohort study

A Cozzi-Lepri, AN Phillips, B Clotet, A Mocroft, L Ruiz… - Aids, 2008 - journals.lww.com
Objective (s): To investigate the relationship between detection of HIV drug resistance by 2
years from starting antiretroviral therapy and the subsequent risk of progression to AIDS and …

Clinical impact of pretreatment human immunodeficiency virus drug resistance in people initiating nonnucleoside reverse transcriptase inhibitor–containing …

S Bertagnolio, L Hermans, MR Jordan… - The Journal of …, 2021 - academic.oup.com
Background Increased access to antiretroviral therapy (ART) has resulted in rising levels of
pretreatment human immunodeficiency virus drug resistance (PDR). This is the first …

Risk of virological failure and drug resistance during first and second-line antiretroviral therapy in a 10-year cohort in Senegal: results from the ANRS 1215 cohort

P De Beaudrap, M Thiam, A Diouf… - JAIDS Journal of …, 2013 - journals.lww.com
Background: In 1998, Senegal launched one of Africa's first antiretroviral therapy (ART)
programs. Since then, the number of treated patients in Africa has substantially increased …