Activity‐based NIR enzyme fluorescent probes for the diagnosis of tumors and image‐guided surgery

H Li, D Kim, Q Yao, H Ge, J Chung, J Fan… - Angewandte …, 2021 - Wiley Online Library
Near‐infrared (NIR) activatable fluorescent probes have been considered to be the effective
edge tools for the investigation of cell biology and disease diagnosis because of their …

Recent advances in enzyme-activated NIR fluorescent probes for biological applications

H Jeong, X Wu, JS Lee, J Yoon - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Enzymes and their regulations are employed as indicators for various diseases, including
cancer. To directly analyze the activity of the enzymes within a biological system, enzyme …

Recent progress on NIR fluorescent probes for enzymes

J Zhao, T Ma, B Chang, J Fang - Molecules, 2022 - mdpi.com
The majority of diseases' biomarkers are enzymes, and the regulation of enzymes is
fundamental but crucial. Biological system disorders and diseases can result from abnormal …

A molecular design strategy toward enzyme-activated probes with near-infrared I and II fluorescence for targeted cancer imaging

R Wang, J Chen, J Gao, JA Chen, G Xu, T Zhu… - Chemical …, 2019 - pubs.rsc.org
The advance of cancer imaging requires innovations to establish novel fluorescent scaffolds
that are excitable and emit in the near-infrared region with favorable Stokes shifts …

Near-infrared fluorescent probes for the detection of cancer-associated proteases

JI Scott, Q Deng, M Vendrell - ACS chemical biology, 2021 - ACS Publications
Proteases are enzymes capable of catalyzing protein breakdown, which is critical across
many biological processes. There are several families of proteases, each of which perform …

Next generation NIR fluorophores for tumor imaging and fluorescence-guided surgery: A review

A Haque, MSH Faizi, JA Rather, MS Khan - Bioorganic & medicinal …, 2017 - Elsevier
Cancer is a group of diseases responsible for the major causes of mortality and morbidity
among people of all ages. Even though medical sciences have made enormous growth …

Near-infrared fluorescent probes for peptidases

J Chin, HJ Kim - Coordination Chemistry Reviews, 2018 - Elsevier
Near-infrared (NIR) fluorescent probes possess a characteristic molecular structure with a
highly conjugated polyene or polynuclear system, thus exhibiting a long emission …

Rapid unperturbed‐tissue analysis for intraoperative cancer diagnosis using an enzyme‐activated NIR‐II nanoprobe

Y Zhan, S Ling, H Huang, Y Zhang… - Angewandte Chemie …, 2021 - Wiley Online Library
Accurate intraoperative tissue identification is critical to tumor surgery. However,
conventional methods are labor‐and time‐intensive, which greatly delay the intraoperative …

Recent advances on activatable NIR‐II fluorescence probes for biomedical imaging

Y Tang, F Pei, X Lu, Q Fan… - Advanced Optical …, 2019 - Wiley Online Library
Newly emerging fluorescence imaging in the second near‐infrared window (NIR‐II, 1000–
1700 nm) permits visualization of deep anatomical features with unprecedented spatial …

Functional near‐infrared fluorescent probes

K Kiyose, H Kojima, T Nagano - Chemistry–An Asian Journal, 2008 - Wiley Online Library
Near‐infrared (NIR) fluorescent probes have attracted much attention, but despite the
availability of various NIR fluorophores, only a few functional NIR probes, that is, probes …