Prion diseases are efficiently transmitted by blood transfusion in sheep

F Houston, S McCutcheon, W Goldmann… - Blood, The Journal …, 2008 - ashpublications.org
The emergence of variant Creutzfeld-Jakob disease, following on from the bovine
spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of …

Transmission of prion diseases by blood transfusion

N Hunter, J Foster, A Chong… - Journal of General …, 2002 - microbiologyresearch.org
Attempts to detect infectivity in the blood of humans and animals affected with transmissible
spongiform encephalopathies (TSEs or prion diseases) have often been inconclusive …

The neuropathologic phenotype of experimental ovine BSE is maintained after blood transfusion

S Sisó, L González, F Houston, N Hunter, S Martin… - Blood, 2006 - ashpublications.org
Iatrogenic transmission by blood transfusion has been described in cases of human variant
Creutzfeldt-Jakob disease (vCJD), experimental ovine bovine spongiform encephalopathy …

Creutzfeldt‐Jakob disease and blood transfusion safety

CR Seed, PE Hewitt, RY Dodd, F Houston… - Vox …, 2018 - Wiley Online Library
Transmissible spongiform encephalopathies (TSE s) are untreatable, fatal neurologic
diseases affecting mammals. Human disease forms include sporadic, familial and acquired …

From mad cows to sensible blood transfusion: the risk of prion transmission by labile blood components in the United Kingdom and in France

JJ Lefrère, P Hewitt - Transfusion, 2009 - Wiley Online Library
Transfusion transmission of the prion, the agent of variant Creutzfeldt‐Jakob disease
(vCJD), is now established. Subjects infected through food may transmit the disease through …

Transfusion transmission of human prion diseases

S Zou, CT Fang, LB Schonberger - Transfusion medicine reviews, 2008 - Elsevier
No transmission through transfusion has been reported for classic Creutzfeldt-Jakob
disease (CJD). Moreover, a series of epidemiological surveillance, case-control, and look …

The risk of transmitting prion disease by blood or plasma products

R Knight - Transfusion and Apheresis Science, 2010 - Elsevier
Various experimental studies have shown infectivity in blood in relation to bovine
spongiform encephalitis (BSE) and variant Creutzfeldt–Jakob disease (vCJD). Human to …

Detection of PrPsc in Blood from Sheep Infected with the Scrapie and Bovine Spongiform Encephalopathy Agents

LA Terry, L Howells, J Hawthorn, JC Edwards… - Journal of …, 2009 - Am Soc Microbiol
The role of blood in the iatrogenic transmission of transmissible spongiform encephalopathy
(TSE) or prion disease has become an increasing concern since the reports of variant …

New-variant Creutzfeldt-Jakob disease: the risk of transmission by blood transfusion

ML Turner, JW Ironside - Blood Reviews, 1998 - Elsevier
New-variant Creutzfeldt-Jakob disease (nvCJD) was first described in the UK in 1996 and is
thought to be related to the consumption of cattle suffering from bovine spongiform …

[HTML][HTML] Variant Creutzfeldt–Jakob disease and its transmission by blood

JW Ironside, MW Head - Journal of Thrombosis and Haemostasis, 2003 - Elsevier
Summary Variant Creutzfeldt–Jakob disease (vCJD) is a novel acquired human prion
disease resulting from human exposure to the agent causing bovine spongiform …