The study objective was to compare the effect of budesonide administered as a nebulized
suspension as compared to a spray with a spacer in adult asthmatics. In a double-blind …

Objective To provide an overview of aerosol drug delivery during mechanical ventilation in
the pediatric and adult populations. Data Sources Published articles and abstracts identified …

Background Since the late 1980s, there has been considerable clinical and academic
interest in the use of continuous aerosolized bronchodilators for the treatment of patients …

The output from a jet nebulizer was analyzed for aerosol profile, solution output, and delivery
of albuterol at three different initial volume fills to determine the changes that occur during …

Inhalation is the preferred route for asthma therapy, since it offers a rapid onset of drug
action, requires smaller doses, and reduces systemic effects compared with other routes of …

The output characteristics of current nebulizer systems are influenced by factors such as
inspiratory flow, temperature and relative humidity of the ambient air as well as surface …

In the last decade, the development of safer, more effective, and longer acting beta2-
adenergic drugs has provided physicians with the means of both preventing and treating …

The mass of aerosol inhaled is primarily a function of the patient's breathing pattern and the
aerosol delivery system. Once inhaled, deposition is governed by factors related to the …

Today there is a general use of aerosols in the treatment of asthma. To understand their
importance it is necessary to know the make-up of an aerosol, physical and chemical factors …

In previous chapters, physicochemical and physiological aspects of lung aerosol-delivery
systems have been discussed. This chapter addresses the route of delivery and the various …