Resveratrol‐mediated apoptosis of hodgkin lymphoma cells involves SIRT1 inhibition and FOXO3a hyperacetylation

R Frazzi, R Valli, I Tamagnini, B Casali… - … journal of cancer, 2013 - Wiley Online Library
Abstract Resveratrol (RSV), a plant‐derived stilbene, induces cell death in Hodgkin
lymphoma (HL)‐derived L‐428 cells in a dose‐dependent manner (IC50= 27 μM, trypan …

Resveratrol (trans‐3, 5, 4′‐trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF‐κB

NP Singh, UP Singh, VL Hegde, H Guan… - Molecular nutrition & …, 2011 - Wiley Online Library
Scope: Understanding the molecular mechanisms through which natural products and
dietary supplements exhibit anticancer properties is crucial and can lead to drug discovery …

Resveratrol inhibits proliferation and promotes apoptosis of osteosarcoma cells

Y Li, CM Bäckesjö, LA Haldosén, U Lindgren - European journal of …, 2009 - Elsevier
The phytoalexin resveratrol has been described to have chemopreventive and
chemotherapeutic effects in several tumor models while its effects on osteosarcoma have …

[HTML][HTML] Resveratrol induces apoptosis by modulating the reciprocal crosstalk between p53 and Sirt-1 in the CRC tumor microenvironment

A Brockmueller, C Buhrmann, P Shayan… - Frontiers in …, 2023 - frontiersin.org
Introduction P53 represents a key player in apoptosis-induction in cancers including
colorectal cancer (CRC) that ranks third worldwide in cancer prevalence as well as mortality …

Resveratrol induces gastric cancer cell apoptosis via reactive oxygen species, but independent of sirtuin1

Z Wang, W Li, X Meng, B Jia - Clinical and Experimental …, 2012 - Wiley Online Library
The currently available chemotherapeutic regimens against gastric cancer are not very
effective, leading to high recurrence and poor survival. Resveratrol is a naturally occurring …

[HTML][HTML] Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activity

SC Chao, YJ Chen, KH Huang, KL Kuo, TH Yang… - Scientific reports, 2017 - nature.com
Chondrosarcoma is a malignant primary bone tumor. Sirtuin-1 (SIRT1), which is a member
of sirtuin family, plays a dual role either in cancer promotion or suppression. There is no …

Resveratrol modifies the expression of apoptotic regulatory proteins and sensitizes non-Hodgkin's lymphoma and multiple myeloma cell lines to paclitaxel-induced …

AR Jazirehi, B Bonavida - Molecular cancer therapeutics, 2004 - AACR
Abstract Resveratrol (trans-3, 4, 5-trihydroxystilbene) has received attention for its potential
chemopreventive and antitumor effects in experimental systems. Recent evidence suggests …

Resveratrol-induced apoptosis in human T-cell acute lymphoblastic leukaemia MOLT-4 cells

V Cecchinato, R Chiaramonte, M Nizzardo… - Biochemical …, 2007 - Elsevier
Resveratrol (RES) is a natural occurring phytoalexin that has been shown to have
chemopreventive activity. Resveratrol acts both by suppressing cell proliferation and …

Resveratrol inhibits proliferation and promotes apoptosis of neuroblastoma cells: role of sirtuin 1

JG Pizarro, E Verdaguer, V Ancrenaz, F Junyent… - Neurochemical …, 2011 - Springer
Resveratrol prolongs lifespan and prevent cancer formation; however, the mechanisms are
not understood. Here we evaluated the cell-cycle inhibition and apoptosis of resveratrol in …

Targeting of cancer cell death mechanisms by resveratrol: a review

X Fu, M Li, C Tang, Z Huang, M Najafi - Apoptosis, 2021 - Springer
Cancer cell death is the utmost aim in cancer therapy. Anti-cancer agents can induce
apoptosis, mitotic catastrophe, senescence, or autophagy through the production of free …