Most bacterial cells are surrounded by a peptidoglycan cell wall that is essential for their
integrity. The major synthases of this exoskeleton are called penicillin-binding proteins …

Control of peptidoglycan assembly is critical to maintain bacterial cell size and morphology.
Penicillin-binding proteins (PBPs) are crucial enzymes for the polymerization of the glycan …

MreC and MreD, along with the actin homologue MreB, are required to maintain the shape
of rod-shaped bacteria. The depletion of MreCD in rod-shaped bacteria leads to the …

RodZ of rod‐shaped bacteria functions to link MreB filaments to the Rod peptidoglycan (PG)
synthase complex that moves circumferentially perpendicular to the long cell axis, creating …

Penicillin-binding proteins (PBPs) are key to the assembly of peptidoglycan, the major
component of the bacterial cell wall. Although several PBP-specific regulatory proteins have …

Most bacterial cells are surrounded by an essential cell wall composed of the net-like
heteropolymer peptidoglycan (PG). Growth and division of bacteria are intimately linked to …

Bacterial cell shape is dictated by the cell wall, a plastic structure that must adapt to growth
and division whilst retaining its function as a selectively permeable barrier. The modulation …

Highlights•Pneumococcal cell division is regulated positively by the MapZ system.•The
MapZ protein marks the division site.•Cell constriction is regulated by MapZ …

S treptococcus pneumoniae is an oval‐shaped G ram‐positive coccus that lives in intimate
association with its human host, both as a commensal and pathogen. The seriousness of …

Multi-protein complexes organized by cytoskeletal proteins are essential for cell wall
biogenesis in most bacteria. Current models of the wall assembly mechanism assume that …