Computational analysis of proteome of H5N1 avian influenza virus to define T cell epitopes with vaccine potential
R Parida, MS Shaila, S Mukherjee, NR Chandra… - Vaccine, 2007 - Elsevier
The existing vaccines against influenza are based on the generation of neutralizing antibody
primarily directed against surface proteins—hemagglutinin and neuraminidase. In this work …
primarily directed against surface proteins—hemagglutinin and neuraminidase. In this work …
Prediction of epitopes in hemagglutinin and neuraminidase proteins of influenza A virus H5N1 strain: a clue for diagnostic and vaccine development
The avian influenza is an important infectious disease of birds. The genome of influenza A
virus was segmented, single-stranded, negative-sense RNA molecules, which encodes …
virus was segmented, single-stranded, negative-sense RNA molecules, which encodes …
A conserved multi-epitope-based vaccine designed by targeting hemagglutinin protein of highly pathogenic avian H5 influenza viruses
The highly pathogenic avian H5N1 influenza viruses have been recognized as a potential
pandemic threat to humans, and to the poultry industry since 1997. H5 viruses consist of a …
pandemic threat to humans, and to the poultry industry since 1997. H5 viruses consist of a …
An immunoinformatics approach in design of synthetic peptide vaccine against influenza virus
N Lohia, M Baranwal - Immunoinformatics, 2020 - Springer
Peptide-based vaccines are an appealing strategy which involves usage of short synthetic
peptides to engineer a highly targeted immune response. These short synthetic peptides …
peptides to engineer a highly targeted immune response. These short synthetic peptides …
Conserved peptides containing overlapping CD4+ and CD8+ T-cell epitopes in the H1N1 influenza virus: an immunoinformatics approach
N Lohia, M Baranwal - Viral Immunology, 2014 - liebertpub.com
Pandemic threats of the H1N1 influenza virus have drawn attention to developing a
universal vaccine against circulating and future strains of this virus. An immunoinformatics …
universal vaccine against circulating and future strains of this virus. An immunoinformatics …
H7N9 influenza outbreak in China 2013: In silico analyses of conserved segments of the hemagglutinin as a basis for the selection of peptide vaccine targets
T Sarkar, S Das, A De, P Nandy… - … Biology and Chemistry, 2015 - Elsevier
The sudden emergence of a human infecting strain of H7N9 influenza virus in China in 2013
leading to fatalities in about 30% of the cases has caused wide concern that additional …
leading to fatalities in about 30% of the cases has caused wide concern that additional …
Immunoinformatic based designing of potential immunogenic novel mRNA and peptide-based prophylactic vaccines against H5N1 and H7N9 avian influenza viruses
Influenza viruses are the most common cause of serious respiratory illnesses worldwide and
are responsible for a significant number of annual fatalities. Therefore, it is crucial to look for …
are responsible for a significant number of annual fatalities. Therefore, it is crucial to look for …
In Silico Identification of Highly Conserved Epitopes of Influenza A H1N1, H2N2, H3N2, and H5N1 with Diagnostic and Vaccination Potential
JE Muñoz-Medina, CJ Sánchez-Vallejo… - BioMed Research …, 2015 - Wiley Online Library
The unpredictable, evolutionary nature of the influenza A virus (IAV) is the primary problem
when generating a vaccine and when designing diagnostic strategies; thus, it is necessary …
when generating a vaccine and when designing diagnostic strategies; thus, it is necessary …
Recent developments in bioinformatics analyses of influenza A virus surface glycoproteins and their biological relevance
A M. Hashem, T M. Doyle, G Van Domselaar… - Current …, 2011 - benthamdirect.com
Influenza A surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA), are the
major targets of neutralizing antibodies which necessitate their inclusion in influenza …
major targets of neutralizing antibodies which necessitate their inclusion in influenza …
Synthetic multi‐epitope peptides identified in silico induce protective immunity against multiple influenza serotypes
GA Stoloff… - European journal of …, 2007 - Wiley Online Library
Influenza causes yearly epidemics of mild disease and, occasionally, pandemics with
millions of fatalities. Currently, no vaccine is effective against all influenza strains. Analysis of …
millions of fatalities. Currently, no vaccine is effective against all influenza strains. Analysis of …