Effect of bronchodilation on expiratory flow limitation and resting lung mechanics in COPD

RL Dellacà, PP Pompilio, PP Walker… - European …, 2009 - Eur Respiratory Soc
Bronchodilator drugs produce variable improvements in forced expiratory volume in 1 s
(FEV1), but larger changes in end-expiratory lung volume (EELV) in chronic obstructive …

Volume effect and exertional dyspnoea after bronchodilator in patients with COPD with and without expiratory flow limitation at rest

E Boni, L Corda, D Franchini, P Chiroli, GP Damiani… - Thorax, 2002 - thorax.bmj.com
Background: A study was undertaken to investigate whether bronchodilators are associated
with less breathlessness at rest and during light exercise in patients with moderate to severe …

Exercise and dyspnoea in COPD

PMA Calverley - European Respiratory Review, 2006 - Eur Respiratory Soc
Dyspnoea provoked either by exercise or during a disease exacerbation is one of the most
feared symptoms of the chronic obstructive pulmonary disease (COPD) patient. It contributes …

Mechanisms for isolated volume response to a bronchodilator in patients with COPD

I Cerveri, R Pellegrino, R Dore… - Journal of Applied …, 2000 - journals.physiology.org
We hypothesized that an altered effect of lung inflation on airway caliber may in part explain
the isolated volume response to bronchodilators, ie, an increase of forced vital capacity …

Assessment of bronchodilator efficacy in symptomatic COPD: is spirometry useful?

DE O'Donnell - Chest, 2000 - Elsevier
Bronchodilator therapy in COPD is deemed successful if it improves ventilatory mechanics to
a degree where effective symptom alleviation and increased exercise capacity are achieved …

Factor analysis of changes in dyspnea and lung function parameters after bronchodilation in chronic obstructive pulmonary disease

C Taube, B Lehnigk, K Paasch… - American journal of …, 2000 - atsjournals.org
Expiratory airway collapse is a characteristic feature in patients with chronic obstructive
pulmonary disease (COPD). We hypothesized that this collapse might mask the effects of …

Relationship between improved airflow limitation and changes in airway calibre induced by inhaled anticholinergic agents in COPD

M Hasegawa, H Makita, Y Nasuhara, N Odajima… - Thorax, 2009 - thorax.bmj.com
Background: Although airflow limitation improved by inhaled anticholinergic drugs varies
among individuals with chronic obstructive pulmonary disease (COPD), the relationship …

[HTML][HTML] Bronchodilator responsiveness and onset of effect with budesonide/formoterol pMDI in COPD

BR Celli, DP Tashkin, SI Rennard, J McElhattan… - Respiratory …, 2011 - Elsevier
BACKGROUND: Chronic obstructive pulmonary disease (COPD) patients are thought to
have limited bronchodilator response, determined by changes in forced expiratory volume in …

Alternative methods for assessing bronchodilator reversibility in chronic obstructive pulmonary disease

J Hadcroft, PMA Calverley - Thorax, 2001 - thorax.bmj.com
BACKGROUND Bronchodilator reversibility testing is recommended in all patients with
chronic obstructive pulmonary disease (COPD) but does not predict improvements in …

Response patterns to bronchodilator and quantitative computed tomography in chronic obstructive pulmonary disease

JS Lee, JW Huh, EJ Chae, JB Seo… - Clinical physiology …, 2012 - Wiley Online Library
Background: Patients with chronic obstructive pulmonary disease (COPD) show different
spirometric response patterns to bronchodilator, such that some patients show improvement …