Quantification of residual disease in chronic myelogenous leukemia patients on interferon-alpha therapy by competitive polymerase chain reaction

A Hochhaus, F Lin, A Reiter, H Skladny, PJ Mason… - 1996 - ashpublications.org
Interferon-alpha (IFN-alpha) induces cytogenetic responses of variable degree in patients
with chronic myelogenous leukemia (CML). We sought to establish the relationship between …

Monitoring the Efficiency of Interferon-α Therapy in Chronic Myelogenous Leukemia (CML) Patients by Competitive Polymerase Chain Reaction.

A HOCHHAUS, LIN Feng, A REITER… - Leukemia …, 1997 - search.ebscohost.com
Interferon α (IFN-α) induces cytogenetic responses of variable degree in patients with CML.
We sought to establish the relationship between BCR-ABL transcript numbers measured by …

[引用][C] Predicting complete cytogenetic response in chronic myelogenous leukemia patients treated with recombinant interferon alpha [letter; comment]

FX Mahon, M Montastruc, C Faberes, J Reiffers - 1994 - ashpublications.org
Fig 1. Cumulative incidence of MCR among the 47 evaluable patients (cumulative
incidences and cytogenetic responses were analyzed by the Kaplan and Meier method and …

Use of quantitative polymerase chain reaction to monitor residual disease in chronic myelogenous leukemia during treatment with interferon.

T Lion, A Gaiger, T Henn, E Hörth, OA Haas, K Geissler… - Leukemia, 1995 - europepmc.org
Interferon-alpha (IFN-alpha) has become a widely used treatment modality in chronic
myelogenous leukemia (CML) and was shown to induce complete hematologic responses …

[PDF][PDF] The mechanism by which chronic myeloid leukemia responds to interferon-α treatment

EY Moawad - Advances in Pharmacology and Pharmacy, 2013 - academia.edu
The goal of this work is to determine the mechanism by which addition of interferon-α (IFN-α)
to Dendritic Cells (DC) grown from Chronic Myeloid Leukemia (CML) patients improves its …

[引用][C] Dose related effectiveness of alpha interferon in chronic myelogenous leukemia

G Gastl, Q Aulitzky, H Tilg, H Huber, H Hausmaninger… - Blut, 1987 - Springer
Recently, Talpaz [1] reported that human interferon alpha (IFN) can induce haematological
remission and cytogenetic improvement in patients with Philadelphia-chromosome-positive …

[PDF][PDF] Long-term molecular response after discontinuation of interferon-alpha in two patients with chronic myeloid leukaemia

E Mauro - Blood Transfusion, 2012 - bloodtransfusion.it
Dear Sir, We would like to take part in the debate about the discontinuation of treatment of
chronic myeloid leukaemia (CML), with particular reference to the Letter to the Editor by …

Should polymerase chain reaction analysis to detect minimal residual disease in patients with chronic myelogenous leukemia be used in clinical decision making?

S Faderl, M Talpaz, HM Kantarjian… - Blood, The Journal of …, 1999 - ashpublications.org
CHRONIC MYELOGENOUS leukemia (CML) is a unique myeloproliferative disorder usually
associated with a distinctive cytogenetic abnormality—the Philadelphia chromosome (Ph) …

Divergent in vivo and in vitro antileukemic activity of recombinant interferon beta in patients with chronic-phase chronic myelogenous leukemia

WE Aulitzky, C Peschel, D Despres, J Aman… - Annals of …, 1993 - Springer
It was the aim of this study to investigate the antileukemic activities of recombinant interferon
beta (rIFN beta) in chronic-phase CML in vitro and in vivo. Nine patients in the early chronic …

[引用][C] MONITORING THE EFFICIENCY OF INTERFERON-ALPHA THERAPY IN CHRONIC MYELOID-LEUKEMIA (CML) PATIENTS BY COMPETITIVE POLYMERASE …

A HOCHHAUS, F LIN… - …, 1995 - … PUBL COLTD BLAKE CTR, STE 200 …