Effect of recombinant interferon alpha-2 on the growth of hematopoetic progenitor cells in chronic myelogenous leukemia and its relationship to the clinical efficacy

D Geissler, W Aulitzky, H Tilg, I Von Lüttichau… - … Leukemia and Interferon …, 1988 - Springer
Abstract α-Interferon (IFN) has recently been evaluated for the treatment of chronic
myelogenous leukemia (CML)[1, 2, 7–9]. Using natural and recombinant DNA-derived IFN-α …

[引用][C] Practical Management of Interferon Therapy and Side Effects

S O'Brien, HM Kantarjian… - BASIC AND CLINICAL …, 1998 - MARCEL DEKKER, INC

Predominantly BCR-ABL negative myeloid precursors in interferon-α treated chronic myelogenous leukemia: a follow-up study of peripheral blood colony-forming …

C Sick, B Schultheis, G Pasternak, I Kottke… - Annals of …, 2001 - Springer
The mechanism and target cell of the life-prolonging effect of interferon-α (IFN-α) in chronic
myelogenous leukemia (CML) are controversial. We studied the influence of IFN-α treatment …

[引用][C] Effect of interferon-alpha (IFN-A) on different lymphocyte subpopulations in patients with chronic myeloid leukemia (CML).

J Cortes, S Sacchi, H Kantarjian, M Talpaz - BLOOD, 1996 - iris.unimore.it
Effect of interferon-alpha (IFN-A) on different lymphocyte subpopulations in patients with
chronic myeloid leukemia (CML)/J., Cortes; Sacchi, Stefano; H., Kantarjian; M., Talpaz.-In …

Clonogenic assay is not predictive but reflects therapeutic efficacy of interferons in the treatment of chronic myelogenous leukemia

UB Wandl, M Kranzhoff, S Seeber, N Niederle - Stem Cells, 1992 - academic.oup.com
Patients with chronic myelogenous leukemia (CML) have been treated with interferon (IFN)
α-2b alone or in combination with IFNγ. In order to predict clinical response to IFN, bone …

Interferon alpha-2c therapy of patients with chronic myelogenous leukemia: long-term results of a multicenter phase-II study

J Thaler, G Gastl, T Fluckinger, D Niederwieser… - Annals of …, 1996 - Springer
In a prospective multicenter phase-II trial 80 patients with Philadelphia (Ph)-positive chronic
myelogenous leukemia (CML) were treated with recombinant interferon (IFN) α-2c …

Combination therapy with interferon alpha‐2b plus low‐dose interferon gamma in pretreated patients with Ph‐positive chronic myelogenous leukaemia

UB Wandl, O Kloke, M Nagel‐Hiemke… - British journal of …, 1992 - Wiley Online Library
Between March 1988 and July 1990, 28 adults with chronic myelogenous leukaemia (CML)
were treated with a combination of recombinant human interferon (IFN) alpha‐2b sc (initial …

In vitro activity of alpha-interferon on granulocyte-macrophage precursors in chronic myeloid leukemia (CML): correlation with clinical responsiveness

MA Santucci, G Visani, D Russo, A Zaccaria… - Leukemia & …, 1992 - Taylor & Francis
Treatment with alpha-interferon (α-IFN) induces an hematologic remission in the majority of
early benign phase chronic myeloid leukemia (CML) patients, and cytogenetic improvement …

A guide to the use of interferon-alpha in the management of chronic myelogenous leukaemia

J Cortes, S O'Brien - BioDrugs, 2000 - Springer
Interferon-alpha (IFNα) can induce major cytogenetic responses in 30 to 40% of patients
with chronic myelogenous leukaemia (CML) and up to 50% when combined with cytarabine …

[引用][C] Cytogenetic Response to Interferon in Chronic Myeloid Leukemia: A Common Denominator of Treatment Outcome

RTJKG DRaghunadhaRao - Abstracts of Asian-Pacific Conference of Tumor Biology …, 2001