Cadherin switch in tumor progression
RB Hazan, RUI Qiao, R Keren… - Annals of the New …, 2004 - Wiley Online Library
The loss of E‐cadherin expression or function in epithelial carcinomas has long been
thought as a primary reason for disruption of tight epithelial cell‐cell contacts and release of …
thought as a primary reason for disruption of tight epithelial cell‐cell contacts and release of …
Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis
RB Hazan, GR Phillips, RF Qiao, L Norton… - The Journal of cell …, 2000 - rupress.org
E-and N-cadherin are calcium-dependent cell adhesion molecules that mediate cell–cell
adhesion and also modulate cell migration and tumor invasiveness. The loss of E-cadherin …
adhesion and also modulate cell migration and tumor invasiveness. The loss of E-cadherin …
N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression
MT Nieman, RS Prudoff, KR Johnson… - The Journal of cell …, 1999 - rupress.org
E-cadherin is a transmembrane glycoprotein that mediates calcium-dependent, homotypic
cell–cell adhesion and plays a role in maintaining the normal phenotype of epithelial cells …
cell–cell adhesion and plays a role in maintaining the normal phenotype of epithelial cells …
Cadherins and the tumour progression: is it all in a switch?
U Cavallaro, B Schaffhauser, G Christofori - Cancer letters, 2002 - Elsevier
Progression to tumour malignancy involves changes in a tumour cell's capabilities to adhere
and communicate with neighboring cells and with its extracellular environment. Correlation …
and communicate with neighboring cells and with its extracellular environment. Correlation …
Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion.
S Islam, TE Carey, GT Wolf, MJ Wheelock… - The Journal of cell …, 1996 - rupress.org
E-cadherin is a transmembrane glycoprotein that mediates calcium-dependent, homotypic
cell-cell adhesion and plays an important role in maintaining the normal phenotype of …
cell-cell adhesion and plays an important role in maintaining the normal phenotype of …
Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness
W Birchmeier, J Behrens - Biochimica et Biophysica Acta (BBA)-Reviews …, 1994 - Elsevier
Cell adhesion in tumors............................................. 1.1. Invasive carcinoma cells exhibit
reduced intercellular adhesion.................... 1.2. The role of the cell adhesion molecule E …
reduced intercellular adhesion.................... 1.2. The role of the cell adhesion molecule E …
The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
G Christofori, H Semb - Trends in biochemical sciences, 1999 - cell.com
E-cadherin-mediated cell–cell adhesion is lost during the development of most epithelial
cancers. Recent evidence indicates that the loss of E-cadherin function, besides causing …
cancers. Recent evidence indicates that the loss of E-cadherin function, besides causing …
[PDF][PDF] Cadherin-mediated cell-cell adhesion and tissue segregation in relation to malignancy
RA Foty, MS Steinberg - International Journal of Developmental …, 2004 - academia.edu
We review evidence concerning the basis for tissue segregation during embryonic
development. This compartmentalization is shown to be an immiscibility phenomenon …
development. This compartmentalization is shown to be an immiscibility phenomenon …
E‐cadherin mediated adhesion system in cancer cells
H Shiozaki, H Oka, M Inoue, S Tamura… - … Journal of the …, 1996 - Wiley Online Library
BACKGROUND Cadherins are the family of functionally related transmembrane
glycoproteins responsible for the Ca2+‐dependent cell–cell adhesion mechanism that is …
glycoproteins responsible for the Ca2+‐dependent cell–cell adhesion mechanism that is …
The functional activity of E-cadherin controls tumor cell metastasis at multiple steps
TY Na, L Schecterson, AM Mendonsa… - Proceedings of the …, 2020 - National Acad Sciences
E-cadherin is a tumor suppressor protein, and the loss of its expression in association with
the epithelial mesenchymal transition (EMT) occurs frequently during tumor metastasis …
the epithelial mesenchymal transition (EMT) occurs frequently during tumor metastasis …