Efficient extracellular vesicles freeze-dry method for direct formulations preparation and use
M Guarro, F Suñer, M Lecina, S Borrós… - Colloids and Surfaces B …, 2022 - Elsevier
Despite the great knowledge achieved in the field of extracellular vesicles (EVs), the short
lifetime of EVs liquid formulation still hampers the transfer of EVs technology to clinical …
lifetime of EVs liquid formulation still hampers the transfer of EVs technology to clinical …
Comparative studies of different preservation methods and relative freeze-drying formulations for extracellular vesicle pharmaceutical applications
Extracellular vesicles (EVs) have been studied for years for their role as effectors and
mediators of cell-to-cell communication and their potential application to develop new and …
mediators of cell-to-cell communication and their potential application to develop new and …
Enhancing the stabilization potential of lyophilization for extracellular vesicles
E Trenkenschuh, M Richter, E Heinrich… - Advanced …, 2022 - Wiley Online Library
Extracellular vesicles (EV) are an emerging technology as immune therapeutics and drug
delivery vehicles. However, EVs are usually stored at− 80° C which limits potential clinical …
delivery vehicles. However, EVs are usually stored at− 80° C which limits potential clinical …
Preserving extracellular vesicles for biomedical applications: consideration of storage stability before and after isolation
F Yuan, YM Li, Z Wang - Drug Delivery, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are nanovesicles released by various cell types. EVs are known
for cell-to-cell communications and have potent biological activities. Despite great progress …
for cell-to-cell communications and have potent biological activities. Despite great progress …
[HTML][HTML] Influence of short term storage conditions, concentration methods and excipients on extracellular vesicle recovery and function
SI Van De Wakker, J Van Oudheusden, EA Mol… - European Journal of …, 2022 - Elsevier
Extracellular vesicles (EVs) are phospholipid bilayer enclosed vesicles which play an
important role in intercellular communication. To date, many studies have focused on …
important role in intercellular communication. To date, many studies have focused on …
[HTML][HTML] Extracellular vesicles as natural, safe and efficient drug delivery systems
Extracellular vesicles (EVs) are particles naturally released from cells, delimited by a lipid
bilayer, carrying functionally active biological molecules. In addition to their physiological …
bilayer, carrying functionally active biological molecules. In addition to their physiological …
[HTML][HTML] Three method-combination protocol for improving purity of extracellular vesicles
T Simon, A Kumaran, DF Veselu, G Giamas - International Journal of …, 2020 - mdpi.com
Extracellular vesicles (EVs) are nanosized structures able to carry proteins, lipids and
genetic material from one cell to another with critical implications in intercellular …
genetic material from one cell to another with critical implications in intercellular …
[HTML][HTML] Extracellular vesicles: The future of therapeutics and drug delivery systems
Extracellular vesicles (EVs) are nanometric size, a cell-derived drug delivery carrier
composed of membrane-bound structures, release into the cellular medium and found in …
composed of membrane-bound structures, release into the cellular medium and found in …
[HTML][HTML] Higher functionality of extracellular vesicles isolated using size-exclusion chromatography compared to ultracentrifugation
EA Mol, MJ Goumans, PA Doevendans… - … , Biology and Medicine, 2017 - Elsevier
Extracellular vesicles (EVs) are nano-sized, lipid bilayer-enclosed particles involved in
intercellular communication. EVs are increasingly being considered as drug delivery …
intercellular communication. EVs are increasingly being considered as drug delivery …
[HTML][HTML] Extracellular vesicle lyophilization for enhanced distribution to the point of care
ME Golan, SL Stice - Extracellular Vesicle, 2024 - Elsevier
Therapeutic extracellular vesicles (EVs) are in clinical trials and if successful, EVs wider use
will be largely affected by costs to patients/insurers and accessibility. EV preservation …
will be largely affected by costs to patients/insurers and accessibility. EV preservation …