Immunopathological characterization of selected mouse models of inflammatory bowel disease: Comparison to human disease

YL Jones-Hall, MB Grisham - Pathophysiology, 2014 - Elsevier
Inflammatory bowel diseases (IBD) are chronic, relapsing conditions of multifactorial
etiology. The two primary diseases of IBD are Crohn's disease (CD) and ulcerative colitis …

Experimental mouse models of inflammatory bowel disease: new insights into pathogenic mechanisms

CO Elson, CT Weaver - Inflammatory bowel disease: from bench to …, 2003 - Springer
Inflammatory bowel disease (IBD) is a term that comprises two chronic inflammatory
diseases of humans, namely ulcerative colitis and Crohn's disease. Despite many years of …

Mouse models of inflammatory bowel disease for investigating mucosal immunity in the intestine

G Bamias, KO Arseneau… - Current Opinion in …, 2017 - journals.lww.com
Animal models of intestinal inflammation continue to be important research tools with high
significance for understanding the pathogenesis of IBD and exploring novel therapeutic …

Mouse models of inflammatory bowel disease

S Wirtz, MF Neurath - Advanced drug delivery reviews, 2007 - Elsevier
Animal models of intestinal inflammation are indispensable for our understanding of the
pathogenesis of Crohn disease and Ulcerative colitis, the idiopathic forms of inflammatory …

An update of research animal models of inflammatory bowel disease

Z Baydi, Y Limami, L Khalki, N Zaid… - The Scientific World …, 2021 - Wiley Online Library
Inflammatory bowel disease (IBD) is a group of chronic disorders that includes two main
disease forms, Crohn's disease, and ulcerative colitis. The understanding of the intestinal …

Do different animal models of IBD serve different purposes?

MB Grisham - Inflammatory bowel diseases, 2008 - academic.oup.com
The relatively recent development of different mouse models of chronic gut inflammation has
advanced dramatically our understanding of the pathogenesis of the inflammatory bowel …

Animal models of inflammatory bowel disease

MEA Borm, G Bouma - Drug Discovery Today: Disease Models, 2004 - Elsevier
Crohn's disease and ulcerative colitis are chronic idiopathic inflammatory disorders of the
gastro-intestinal tract. Although the exact etiology of these inflammatory bowel diseases …

Overview of mouse models of inflammatory bowel disease and their use in drug discovery

JR Maxwell, JL Viney - Current protocols in pharmacology, 2009 - Wiley Online Library
Inflammatory bowel disease (IBD), a condition that affects millions of individuals,
encompasses two distinct conditions: Crohn's disease (CD) and ulcerative colitis (UC). CD is …

Animal models of inflammatory bowel disease

MB Grisham - Current Opinion in Gastroenterology, 1993 - journals.lww.com
A major limitation in understanding the pathogenetic mechanisms responsible for the
intestinal or colonic mucosal injury and dysfunction observed in inflammatory bowel disease …

Experimental models of inflammatory bowel disease

CO Elson, RB Sartor, GS Tennyson, RH Riddell - Gastroenterology, 1995 - Elsevier
T he inflammatory bowel diseases (IBDs), Crohn's dis-ease and ulcerative colitis, are
multifactorial disorders whose etiology remains unknown. Although the exact pathogenesis …