A lack of effective treatment is one of the main factors contributing to gastric cancer–related
death. Discovering effective targets and understanding their underlying anti-cancer …

Abstract Transient Receptor Potential Melastatin-2 (TRPM2) ion channel is emerging as a
great therapeutic target in many types of cancer, including gastric cancer–a major health …

The calcium-permeable cation channel TRPM8 (transient receptor potential melastatin 8) is
a member of the TRP superfamily of cation channels that is upregulated in various types of …

Purpose Transient receptor potential melastatin 2 (TRPM2), a calcium-permeable ion
channel, is shown as a prognostic marker candidate in prostate cancer (PCa) and an …

Previous studies have demonstrated that autophagy tightly regulates apoptosis. However,
the underlying mechanism whereby autophagy regulates apoptosis remains unclear. Here …

Transient receptor potential melastatin 2 (TRPM2) ion channel has an essential function in
maintaining cell survival following oxidant injury. Here, we show that TRPM2 is highly …

High intracellular levels of reactive oxygen species (ROS) cause oxidative stress that results
in numerous pathologies, including cell death. Transient potential receptor melastatin-2 …

Abstract Background and Purpose Transient receptor potential melastatin type‐8 (TRPM8) is
a cold‐sensitive cation channel protein belonging to the TRP superfamily of ion channels …

Esophageal cancer is seen with increasing incidence, but the underlying mechanism of
esophageal cancer is still unknown. Transient receptor potential melastatin (TRPM) is non …

Background: Cisplatin is a widely used anti-tumor agent but its use is frequently limited by
nephrotoxicity. Transient receptor potential melastatin 2 (TRPM2) is a non-selective cation …