Regulatory roles of long noncoding RNAs implicated in cancer hallmarks

J Wang, X Zhang, W Chen, X Hu, J Li… - International journal of …, 2020 - Wiley Online Library
Cancer cells acquire numerous biological properties (designated “cancer hallmarks”), such
as cell survival and energy metabolism, that facilitate tumor growth and metastatic …

[HTML][HTML] Long noncoding RNAs in cancer: mechanisms of action and technological advancements

N Bartonicek, JLV Maag, ME Dinger - Molecular cancer, 2016 - Springer
The previous decade has seen long non-coding RNAs (lncRNAs) rise from obscurity to
being defined as a category of genetic elements, leaving its mark on the field of cancer …

[HTML][HTML] Long non-coding RNAs: Tools for understanding and targeting cancer pathways

GK Pandey, C Kanduri - Cancers, 2022 - mdpi.com
Simple Summary Long non-coding RNA (lncRNA) is a type of RNA molecule that show
striking resemblance to mRNA in terms of synthesis and structure but lacks protein coding …

[HTML][HTML] The functional role of long non-coding RNA in human carcinomas

EA Gibb, CJ Brown, WL Lam - Molecular cancer, 2011 - Springer
Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …

A mechanistic view of long noncoding RNAs in cancer

L Winkler, N Dimitrova - Wiley Interdisciplinary Reviews: RNA, 2022 - Wiley Online Library
Long noncoding RNAs (lncRNAs) have emerged as important modulators of a wide range of
biological processes in normal and disease states. In particular, lncRNAs have garnered …

Long noncoding RNAs in cancer and therapeutic potential

A Renganathan, E Felley-Bosco - Long Non Coding RNA Biology, 2017 - Springer
Long noncoding RNAs (lncRNAs) are the major elements of the mammalian transcriptome
that is emerging as a central player controlling diverse cellular mechanisms. Most of the well …

[HTML][HTML] Exploring the mechanisms behind long noncoding RNAs and cancer

MM Balas, AM Johnson - Non-coding RNA research, 2018 - Elsevier
Over the past decade, long noncoding RNAs (lncRNAs) have been identified as significant
players in gene regulation. They are often differentially expressed and widely-associated …

[HTML][HTML] Long noncoding RNAs in development and cancer: potential biomarkers and therapeutic targets

R Fatima, VS Akhade, D Pal, SMR Rao - Molecular and cellular therapies, 2015 - Springer
Long noncoding RNAs are emerging as key players in various fundamental biological
processes. We highlight the varied molecular mechanisms by which lncRNAs modulate …

Emerging roles of long non‐coding RNA in cancer

A Sanchez Calle, Y Kawamura, Y Yamamoto… - Cancer …, 2018 - Wiley Online Library
Since comprehensive analysis of the mammalian genome revealed that the majority of
genomic products are transcribed in long non‐coding RNA (lnc RNA), increasing attention …

[HTML][HTML] A central role for long non-coding RNA in cancer

SA Mitra, AP Mitra, TJ Triche - Frontiers in genetics, 2012 - frontiersin.org
Long non-coding RNAs (ncRNAs) have been shown to regulate important biological
processes that support normal cellular functions. Aberrant regulation of these essential …