There is great controversy as to whether alteration of the p53 gene adversely affects survival
of non-small cell lung cancer patients. The aim of this study was to qualitatively review the …

The role of p53, as a prognostic factor for survival in lung cancer, is controversial and the
purpose of the present systematic review of the literature is to determine this effect …

PURPOSE This study was conducted to evaluate the prognostic significance of p53
abnormalities in primary, resected non-small-cell lung cancer (NSCLC). PATIENTS AND …

The association of p53 abnormalities with the prognosis of patients with non-small cell lung
carcinoma (NSCLC) has been extensively investigated to date, however, this association is …

Background: Inactivation of the p53 tumor suppressor gene (also known as TP53) through a
point mutation and/or loss of heterozygosity is one of the most common genetic changes …

Abstract p53 alterations are the most common genetic lesions observed in lung cancers.
Because of the limited size of individual studies, the distributions of p53 alterations by …

This study was performed to clarify the different effects of each mutant exon of p53 as
indicators of a poor prognosis in patients with non-small cell lung cancer (NSCLC). Tumor …

The importance of p53 mutations in the pathogenesis of human lung carcinoma is well
established, but it is still controversial whether the presence of p53 mutations or …

We investigated the correlation of p53 abnormalities with survival in 85 patients with non-
small cell lung cancer (NSCLC) who had undergone resection with curative intent as part of …

Background: The p53 gene is frequently mutated in non-small-cell lung cancer (NSCLC);
however, the effect of p53 gene mutations on patient prognosis remains unclear. Therefore …