Prognostic significance of p53 alterations in patients with non-small cell lung cancer: a meta-analysis
T Mitsudomi, N Hamajima, M Ogawa… - Clinical Cancer Research, 2000 - AACR
There is great controversy as to whether alteration of the p53 gene adversely affects survival
of non-small cell lung cancer patients. The aim of this study was to qualitatively review the …
of non-small cell lung cancer patients. The aim of this study was to qualitatively review the …
Role of p53 as a prognostic factor for survival in lung cancer: a systematic review of the literature with a meta-analysis
E Steels, M Paesmans, T Berghmans… - European …, 2001 - Eur Respiratory Soc
The role of p53, as a prognostic factor for survival in lung cancer, is controversial and the
purpose of the present systematic review of the literature is to determine this effect …
purpose of the present systematic review of the literature is to determine this effect …
Prognostic significance of abnormal p53 accumulation in primary, resected non-small-cell lung cancers.
M Nishio, T Koshikawa, T Kuroishi… - Journal of clinical …, 1996 - ascopubs.org
PURPOSE This study was conducted to evaluate the prognostic significance of p53
abnormalities in primary, resected non-small-cell lung cancer (NSCLC). PATIENTS AND …
abnormalities in primary, resected non-small-cell lung cancer (NSCLC). PATIENTS AND …
Correlation between the status of the p53 gene and survival in patients with stage I non-small cell lung carcinoma
Y Tomizawa, T Kohno, T Fujita, M Kiyama, R Saito… - Oncogene, 1999 - nature.com
The association of p53 abnormalities with the prognosis of patients with non-small cell lung
carcinoma (NSCLC) has been extensively investigated to date, however, this association is …
carcinoma (NSCLC) has been extensively investigated to date, however, this association is …
Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer
T Mitsudomi, T Oyama, T Kusano… - JNCI: Journal of the …, 1993 - academic.oup.com
Background: Inactivation of the p53 tumor suppressor gene (also known as TP53) through a
point mutation and/or loss of heterozygosity is one of the most common genetic changes …
point mutation and/or loss of heterozygosity is one of the most common genetic changes …
Meta-Analyses of p53 Tumor Suppressor Gene Alterations and Clinicopathological Features in Resected Lung Cancers
MC Tammemagi, JR McLaughlin, SB Bull - Cancer Epidemiology Biomarkers …, 1999 - AACR
Abstract p53 alterations are the most common genetic lesions observed in lung cancers.
Because of the limited size of individual studies, the distributions of p53 alterations by …
Because of the limited size of individual studies, the distributions of p53 alterations by …
Mutations in exon 7 and 8 of p53 as poor prognostic factors in patients with non-small cell lung cancer
C Huang, T Taki, M Adachi, T Konishi, M Higashiyama… - Oncogene, 1998 - nature.com
This study was performed to clarify the different effects of each mutant exon of p53 as
indicators of a poor prognosis in patients with non-small cell lung cancer (NSCLC). Tumor …
indicators of a poor prognosis in patients with non-small cell lung cancer (NSCLC). Tumor …
p53 Null Mutations Undetected by Immunohistochemical Staining Predict a Poor Outcome with Early-Stage Non-Small Cell Lung Carcinomas
T Hashimoto, Y Tokuchi, M Hayashi, Y Kobayashi… - Cancer research, 1999 - AACR
The importance of p53 mutations in the pathogenesis of human lung carcinoma is well
established, but it is still controversial whether the presence of p53 mutations or …
established, but it is still controversial whether the presence of p53 mutations or …
p53 immunostaining positivity is associated with reduced survival and is imperfectly correlated with gene mutations in resected non-small cell lung cancer: A …
We investigated the correlation of p53 abnormalities with survival in 85 patients with non-
small cell lung cancer (NSCLC) who had undergone resection with curative intent as part of …
small cell lung cancer (NSCLC) who had undergone resection with curative intent as part of …
p53 mutations and survival in stage I non-small-cell lung cancer: results of a prospective study
SA Ahrendt, Y Hu, M Buta… - Journal of the …, 2003 - academic.oup.com
Background: The p53 gene is frequently mutated in non-small-cell lung cancer (NSCLC);
however, the effect of p53 gene mutations on patient prognosis remains unclear. Therefore …
however, the effect of p53 gene mutations on patient prognosis remains unclear. Therefore …
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